A number of peripheral blood analytes have been proposed as potential biomarkers of post-traumatic stress disorder (PTSD). Few studies have investigated whether observed changes in biomarkers persist over time. The aim of this study was to investigate the association of combat-related chronic PTSD with a wide array of putative PTSD biomarkers and to determine reliability of the measurements, i....

OBJECTIVE To assess whether adrenocortical function was compromised in patients with active tuberculosis (TB) during the first 5 days of therapy with either a rifampicin-based or ciprofloxacin-based regimen. DESIGN Patients were randomised into two groups of 10 each. Adrenocortical function was compared in both groups by the measurement of biochemical indices, electrolytes, osmolality and pit...

BACKGROUND The purpose of this study was to investigate the effect of prolonged stress on the salivary adrenal hormones (cortisol, dehydroepiandrosterone [DHEA], DHEA-sulfate [DHEA-S]) of individuals with irritable bowel syndrome (IBS). METHODS The participants were female college students, including 10 with IBS and 16 without IBS (control group), who were scheduled for a 2-week teaching prac...

Background: Increased stress levels are associated with various health issues due to the dysregulation of HPA axis, more so when is chronic in nature.As DHEA-S a catabolic hormone may be involved long term diseases like early ageing, hypertension, cancer and other Objectives: The aim this study was see effect perceived subset healthy population male female volunteers who willingly participated ...

Basal levels of monoamines and DHEA in four main limbic brain regions were measured in prepubertal Wistar Kyoto (WKY) rats (a putative animal model of childhood depression). Basal levels of "Brain-Derived Neurotrophic Factor (BDNF)" were also determined in two regions in the hippocampus, compared with Wistar strain controls. In the second phase, we examined the responsiveness of prepubertal WKY...

COVID-19 is a recent respiratory illness with high morbidity and mortality; therefore, the study characterization of blood markers associated improvement or deterioration patients are crucial. This compared levels interleukin 6 (IL-6), procalcitonin (PCT), D-dimer, cortisol, dehydroepiandrosterone sulfate (DHEA-S), c-reactive protein (CRP), 25-OH vitamin D, anti-SARS-CoV-2 IgG antibodies, virem...

Background: This study aimed to estimate the prevalence of osteoporosis among patients with adrenal Cushing’s syndrome (ACS) and disease (CD), investigate whether there is a difference in degree between both groups; if so, what factors may be responsible for this variation. Methods: cross-sectional which data from 19 CD eight ACS were analyzed. Osteoporosis was assessed using bone mineral densi...

In many species, territorial behavior is limited to the breeding season and is tightly coupled to circulating gonadal steroid levels. In contrast, both male and female red squirrels (Tamiasciurus hudsonicus) are highly aggressive in both the breeding and non-breeding seasons in defense of food stores on their individual territories throughout the boreal and northern forests of North America. De...