Continuous glucose monitoring (CGM) is a method of testing in which sensor inserted into the skin and continuously monitors interstitial concentrations. Real-time continuous (rtCGM) systems automatically measure display recent value.
 Evidence suggests that rtCGM may improve hemoglobin A1C time range adults pediatric patients with type 1 diabetes, but this uncertain.
 Limited e...

OBJECTIVE Islet immunity and beta cell reserve status were utilized to classify persons with ketoacidosis as the initial manifestation of diabetes. The clinical features of the various diabetes classes were also characterized. DESIGN Prospective cross sectional study. SETTING Nelson Mandela Academic Hospital, Mthatha, Eastern Cape Province, South Africa. PATIENTS Indigenous Black South Af...

Introduction. Diabetes mellitus patients are a vulnerable group of people who prone to getting infected with severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). The has high binding affinity angiotensin-converting enzyme receptor, which allows efficient host cell entering, prolonged retention, and possibility insulin resistance ketoacidosis development. Case outline. We describe case...

D iabetic ketoacidosis in adolescents can be a cause of severe morbidity and mortality, especially if unrecognized at the time of first diagnosis (1). We present a 15-year-old girl who was initially treated for “diabetic ketoacidosis” with further worsening of her general condition. This delayed recovery, coupled with focused investigations, finally led us to a diagnosis and the appropriate man...

OBJECTIVE To describe the clinical course of individuals with idiopathic type 1 diabetes after a mean of 5 years from diagnosis and to compare glycemic control between those treated with diet and/or oral agents and those treated with insulin at follow-up. RESEARCH DESIGN AND METHODS Medical records of patients with new-onset diabetes, who presented with unprovoked diabetic ketoacidosis, were ...

7 Assal JP, Aoki TT, Manzano FM, Kozak GP. Metabolic effects of sodium bicarbonate in the management of diabetic ketoacidosis. Diabetes 1974;23 :405-11. 8 Bureau MA, Begin R, Berthianne Y, Shapcott D, Khoury K, Gagnon N. Cerebral hypoxia from bicarbonate infusion in diabetic acidosis. J Pediatr 1980;96: 968-73. 9 Nattrass M, Hale PJ. Clinical aspects of diabetic ketoacidosis. In: Nattrass M, Sa...

OBJECTIVE Neonatal diabetes is a heterogeneous group of disorders with diabetes manifestation in the first 6 months of life. The most common etiology in permanent neonatal diabetes is mutations of the ATP-sensitive K(+) channel subunits; in transient neonatal diabetes, chromosome 6q24 abnormalities are the most common cause. RESEARCH DESIGN AND METHODS We report a sporadic case of diabetes wi...

OBJECTIVE To estimate medical expenditures attributable to diabetes ketoacidosis (DKA) and severe hypoglycemia among privately insured insulin-treated U.S. youth with diabetes. RESEARCH DESIGN AND METHODS We analyzed the insurance claims of 7,556 youth, age ≤ 19 years, with insulin-treated diabetes. The youth were continuously enrolled in fee-for-service health plans, and claims were obtained...

D iabetic ketoacidosis (DKA), a hallmark of type 1 diabetes, is the result of uncontrolled production of ketone bodies (3-hy-droxybuturate and acetoacetic acid), leading to a lowering of blood pH (1). Ketogenesis in the liver is triggered by low levels of insulin and high levels of glucagon. In addition, other stress hormones (epinephrine, growth hormone, and cortisol), together with lack of in...