Diabetic neuropathic foot ulcers represent a serious health care burden to patients and to society. While the management of chronic diabetic foot ulcers has improved in recent years, it remains a frustrating problem for a variety of clinicians. This review examines the scientific underpinnings supporting the use of becaplermin (Regranex((R)); Ortho-McNeil Pharmaceutical, Raritan, NJ), or recomb...

The aim of the present study was to investigate the effect of local insulin injection on granulation tissue formation in the wounds of patients with diabetic foot ulcer. Thirty-two patients with diabetic foot ulcer were randomly divided into an insulin (n=18) and a control (n=14) group. In the diabetic foot ulcer wound, the insulin group were administered insulin and the control group were admi...

We investigated the relationship between serum cystatin C levels and the prognosis of diabetic foot ulcerations (DFU). A population-based cohort study involving 1018 patients with type 2 diabetes was conducted. These patients recruited and divided into two groups: nondiabetic foot ulcer group (NDF, n = 865, 85.5%) and diabetic foot ulcer group (DFU, n = 147, 14.5%).After a 1-year-follow-up, DFU...

Aim: Accurate classification of diabetic foot ulcers is essential for inter-clinician communication, assessment of healing tendency, and determination of treatment options. Ulcer classification is performed by many different caregivers involved, but their agreement is unclear. The aim of this study was to assess the inter-observer agreement (IOA) of the most commonly used classification systems...

The current study have been included 250 samples diabetic foot ulcer patients attending in Al-Diwaniyah Teaching Hospital and private clinics at a period of from beginning October 2021 to February 2022, Isolates were identified by morphological form on blood agar macConkey agar, traditional biochemical tests then confirmed Vitek 2 system.

Background Diabetic foot complications are the most serious and costly problem of Diabetes Mellitus affecting substantially the quality of life of these patients. People with diabetic foot ulcers experience severe restrictions on daily life as a result of the ulcer. They face social isolation due to reduced mobility, they require frequent clinical treatment and constant caution to ensure that e...

BACKGROUND AND OBJECTIVE: Diabetic foot ulcer is a major complication caused by diabetes. Electrical stimulation is considered as an efficient modality of diabetic wound healing. This study aimed to investigate the effects of direct-current stimulation of cathodal on skin temperature and acceleration of ischemic diabetic foot ulcer closing. METHODS: This randomized, single-blinded, clinical tri...

Objective. The effect of a proprietary formulation of trans-resveratrol (t-RSV) on manifestations of diabetic foot syndrome (DFS) was studied in type 2 diabetic patients with newly diagnosed diabetic foot ulcers. Method. Placebo-controlled, examiner-blinded, parallel-group randomized controlled pilot clinical trial (ACTRN Clinical Trial Registry number 12610000629033) involving 24 patients with...