INTRODUCTION Bisphenol A (BPA) is an ubiquitous environmental toxin that is also found in dialyzers. Online hemodiafiltration (OL-HDF) more efficiently clears high molecular weight molecules, and this may improve BPA clearance. However, the BPA contents of dialysis membranes may be a source of BPA loading during OL-HDF. METHODS A prospective study assessed plasma BPA levels in OL-HDF patients...

Sir, Haemodialysis (HD) patients have a high prevalence of hepatitis C virus (HCV) infection due to blood transfusions or nosocomial transmission w1,2x; however, the clinical course of HCV-associated liver disease in HD patients is usually mild w3,4x. Recent studies have described a consistent reduction of plasma HCV-RNA levels after dialysis w5–7x, independently of the membranes and anticoagul...

Despite improvements in dialysis technology, including the development of novel biocompatible membranes and ultrapure dialysate, uraemia-associated pruritus (UP) remains a common and significant public health issue [1]. Not only does this distressing symptom profoundly impact on the quality of life and sleep, but recent evidence shows that pruritus is also associated with poor patient outcome. ...

Kidney replacement therapy (KRT) is a term used to encompass life-supporting treatments for kidney failure. except transplantation replaces nonendocrine functions in patients with Researchers have noted that dialysis, which one of the most common KRT used, cannot compensate all tasks performed by kidney, and thus ‘Kidney support therapy’ has been suggested be better name. Support function moder...

the gas separation performance of commercial ceramic titania and hybrid silica (hybsi®) membranes was assessed using the gas permeation and permporometry methods. results indicated that the hybsi® membranes have a hybrid surface containing regions covered by a polymeric matrix and others with inorganic pores. these membranes have high h2 selectivity, which increases significantly with temperatu...

The aim of this study was to evaluate the effect of both uremia itself and hemodialysis (HD) membranes on the induction of apoptosis. Four groups of subjects were evaluated: 21 nondialyzed (Non-D) patients, 10 continuous ambulatory peritoneal dialysis (CAPD) patients, and 53 HD patients who were on hemophan, cuprophan, cellulose acetate, AN69, and polysulfone; control subjects were nine healthy...