THE PITUITARY GLAND This is a small, bean-shaped structure that lies at the base of the brain within the confines of the sella turcica. It is connected to the hypothalamus by a "stalk," composed of axons extending from the hypothalamus. The pituitary is composed of two morphologically and functionally distinct components: the anterior lobe (adenohypophysis) and the posterior lobe (neurohypophys...

Abstract Introduction The extended endoscopic approach (EEA) provides direct access for resection of tuberculum sellae (TSM) and olfactory groove meningiomas (OGM) but is associated with cerebrospinal fluid (CSF) leak in up to 25% patients. To evaluate the impact improved skull base reconstructive techniques, we assessed published CSF percentages EEA over last two decades. Method Random-effects...

chondrosarcoma is a mesenchymal tumor composed of tumor cells producing cartilage. it is more common in older age and often affects the axial skeleton. we report a rare case of chondrosarcoma mimicking a sellar and suprasellar mass with parasellar extension. a 40 yr woman presented with decreasing visual acuity and headache. magnetic resonance (mr) image revealed a cystic sellar and suprasellar...

The relationship between the saccharide chain on the endothelial cell surface and the permeability of intracerebral blood vessels has been studied. In the present study, wheat germ agglutinin (WGA) was perfused into capillaries in the area postrema of the normal Mongolian gerbil, where the blood brain barrier (BBB) is known to lack, and into intracerebral blood vessels, the BBB of which had bee...