LES pressure increase following diaphragmatic contraction as a pinch-cock action acts as one of the barrier mechanism for gastroesophageal reflux. In achalasia patients, incomplete LES relaxation following wet swallow is one of the characteristic manometric findings, along with loss of peristalsis. On the other hand, it has been reported that swallowing effort or esophageal distention have no e...

One of the limiting factors for high resolution magnetic resonance coronary angiography (MRCA) is the motion of the heart during breathing. Current approaches use mainly motion correction in one dimension. We aimed to determine the relation between diaphragmatic motion and cardiac motion as well as the potential influence from external restraints reducing thoracical anterior posterior (AP) moti...

Vassilakopoulos T, Hussain SN. Ventilatory muscle activation and inflammation: cytokines, reactive oxygen species, and nitric oxide. J Appl Physiol 102: 1687–1695, 2007. First published December 21, 2006; doi:10.1152/japplphysiol.01273.2006.— Strenuous diaphragmatic contractions that are induced by inspiratory resistive breathing initiate an inflammatory response that involves the elevation of ...

Dyspnea and reduced exercise capacity, caused, in part, by respiratory muscle dysfunction, are common symptoms in patients with heart failure (HF). However, the etiology of diaphragmatic dysfunction has not been identified. To investigate the effects of HF on diaphragmatic function, models of HF were surgically induced in CD-1 mice by transverse aortic constriction (TAC) and acute myocardial in...

OBJECTIVE We investigated the benefit of diaphragmatic plication for weaning from mechanical ventilation in these adult patients. PATIENTS AND METHODS Four patients underwent diaphragmatic plication for difficulty of weaning from mechanical ventilation due to diaphragmatic paralysis. They were all men with an average age of 70.5 +/- 6.3 years. Three of the patients had undergone cardiac surge...

Right sided traumatic diaphragmatic rupture in children is uncommon and may escape early detection. Missed injuries are associated with high mortality and morbidity due to incarceration and strangulation of abdominal viscera. We report a 15-month-old child with blunt trauma chest and abdomen, who presented with bilateral hemothoraces and liver laceration seven days after the incident. Diagnosis...

Entrapment of renal artery by the diaphragmatic crus is a rare cause of renal artery stenosis. Spiral computed tomography angiography provides a definitive diagnosis and shows the precise relationship of the artery to the diaphragmatic crus. The authors present a case of hypertension developing in a young 20-year-old female due to entrapment of the left renal artery by the diaphragmatic crus. T...

OBJECTIVE Previous muscle activity can alter muscle contractility and lead to strength underestimation or overestimation in functional measurements. The objective of this study was to evaluate changes in the maximum pressure produced by the diaphragm after different series of spontaneous near-to-maximal isometric contractions. METHODS Duplicate studies were performed on 6 dogs with a mean (SD...

conclusions from this experience, we argue that in the right circumstances a completely minimally invasive approach can be taken for synchronous congenital diaphragmatic hernias. case presentation in this case report we have a 2-day-old who developed respiratory distress and on ct scan was found to have a congenital diaphragmatic hernia (cdh) or eventration. this patient is ideal for this case ...

447 September 2014 “ EXPIRATION and slow decrease of light together reaching minimum together ... in about 10 s and immediately cry as before. Silence and hold for about 5 s.” In the script for his late play “Breath,” Samuel Beckett conveys in sound and light his awareness of long and vital expiratory times. His personal experience with emphysema might have provided some of the inspiration. In ...