We have found, in previous studies in vitro using skeletal derived cell cultures, that mid-region fragments of human parathyroid hormone (hPTH) stimulate [3H]thymidine incorporation into DNA and increase the specific activity of the brain-type isoenzyme of creatine kinase (CK). These changes occurred without an increase in cyclic AMP formation which is linked to bone resorption. In this study, ...

Humeral diaphysis fractures are one of the frequent components low-energy trauma in people different age and gender groups with comorbid pathology. Pathological autoimmune trophic processes that disrupt reparative capabilities body have a negative impact on formation connective tissue. The purpose this study is to identify peculiarities treatment for humeral patients Methods Material. 42 fractu...

We have read with interest the article of Prof. J.-Y. Reginster entitled ‘Treatment of Bone in Elderly Subjects: Calcium, Vitamin D, Fluor, Bisphosphonates, Calcitonin’ [1], recently published in Hormone Research, and have the following comments regarding bisphosphonates, which have been the subject of studies in our laboratory for the last 9 years. We think that it would be more useful to clas...

The first objective of this study was to experimentally determine surface bone strain magnitudes and directions at the donor site for bone grafts, the site predisposed to stress fracture, the medial and cranial aspects of the transverse cross section corresponding to the stress fracture site, and the middle of the diaphysis of the humerus of a simplified in vitro laboratory preparation. The sec...

Knowledge of the forces that act upon the equine humerus while the horse is standing and the resulting strains experienced by the bone is useful for the prevention and treatment of fractures and for assessing the proximolateral aspect of the bone as a site for obtaining autogenous bone graft material. The first objective was to develop a mathematical model to predict the loads on the proximal h...