Bacteroides fragilis is an opportunistic pathogen which can cause life threatening infections in humans and animals. The ability to adhere to components of the extracellular matrix, including collagen, is related to bacterial host colonisation. Collagen Far Western analysis of the B. fragilis outer membrane protein (OMP) fraction revealed the presence two collagen adhesin bands of ∼ 31 and ∼ 34...

Bacteroides fragilis is a Gram-negative obligate anaerobe frequently isolated from clinical specimens and sometimes causes severe septicemia in compromised hosts. Increasing interest has been shown in the enterotoxigenicity and drug resistance of B. fragilis in the field of medical microbiology. We previously reported rapid detection of this anaerobe by nested PCR targeting a neuraminidase-enco...

Collagenous colitis, which is clinically characterized by chronic non-bloody diarrhea, is a variant of microscopic colitis. It can be diagnosed on histological grounds, with thickening of the subepithelial collagen layer [1–3]. The colonic mucosa is usually endoscopically normal, although minor abnormalities such as edema or erythema can be seen [2,3]. Serious complications are rare. A 69-year-...

Rabbit tracheal explants supporting growth of inoculated Bacteroides fragilis in air were shown to keep low oxygen tension. Treating the explants with sodium azide induced high oxygen tension and arrested reversibly the growth of B. fragilis.

In their excellent review of the classification of carbapenemhydrolyzing metallo-b-lactamases, Rasmussen and Bush (6) proposed that such enzymes produced by Bacteroides fragilis should be assigned to a new functional subgroup, 3a. The characteristics of b-lactamases from three B. fragilis strains were cited and included those from B. fragilis QMCN3 and B. fragilis QMCN4 (7, 8). To avoid confusi...

conclusions: in the present study, we have figured out that a number of the important anaerobic infections treatment antibiotics have lost partly or totally their effectiveness on b. fragilis. background: bacteroides fragilis are among the most important anaerobic bacteria behind most of the anaerobic infections. they have acquired resistance to essential treatment antibiotics of anaerobic infe...

Monoclonal antibodies (MoAbs) to the lipopolysaccharide (LPS) of Bacteroides fragilis were produced by immunizing mice before hybridization with bacterial outer membranes solubilized with Triton X-100. Nineteen stabile clones were established. They all produced antibodies that reacted more strongly with purified B. fragilis LPS than with crude sonicated antigen in an enzyme immunoassay. Four Mo...

Antisera against seven strains of Bacteroides fragilis subspecies fragilis were produced from dense suspensions of whole cells. These sera exhibited high agglutination titers with homologous antigens. Reciprocal cross-reactions in agglutination tests with each immunizing strain yielded lower titers. Both the indirect and direct fluorescent-antibody techniques were used to evaluate these reagent...

Bacteroides fragilis is an anaerobic bacterial species that is involved in gynecological infections and pathology. The incidence of vaginal carriage is largely unknown, and in order to study this, 120 pregnant women attending a general hospital for delivery were examined. Cultures were positive for eight of these women (6.6%). Interestingly, potential clonal relatedness could be demonstrated am...