نتایج جستجو برای: dihydrotestosterone

تعداد نتایج: 2392  

2006
Nicholas Bruchovsky Paul S. Rennie Navdeep Otal Adrian Vanson Martin Giles Hugh Pontifex

Several parameters of androgen action were measured in hormone-dependent Shionogi carcinoma cells during phases of growth, regression, and recurrence. In the parental C1 line under steady state conditions, dihydrotestosterone is localized exclu sively in the nucleus while testosterone is confined almost entirely to the cytoplasm. After castration, the concentration of testos terone declines mor...

Journal: :Cancer research 1984
W D Heston D Kadmon D F Covey W R Fair

The uptake of exogenously administered radiolabeled polyamines by a rat prostate-derived tumor line, the Dunning R3327 MAT-Lu, and various normal tissues was studied. Pretreatment of tumor cells in vitro with alpha-difluoromethylornithine (DFMO), a polyamine synthesis inhibitor, resulted in a markedly enhanced uptake of both [14C]putrescine and [14 C]spermidine. The in vitro uptake of [14C]putr...

Journal: :Journal of neuroendocrinology 2000
J Godwin V Hartman P Nag D Crews

Sex and species differences in androgenic regulation of steroid hormone receptor mRNAs were examined in the diencephalon of two species of whiptail lizards: Cnemidophorus inornatus is a sexual species and the direct evolutionary ancestor to Cnemidophorus uniparens, an all-female parthenogenetic species. Lizards were gonadectomized and treated with different doses of either aromatizable testoste...

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