نتایج جستجو برای: diphtheria toxoid purification and characterization

تعداد نتایج: 16903098  

2014
Ali Eslamifar Amitis Ramezani Mohammad Banifazl Masoomeh Sofian Fatemeh- Alsadat Mahdaviani Farhad Yaghmaie Arezoo Aghakhani

BACKGROUND AND OBJECTIVES Tetanus and diphtheria are vaccine-preventable, infectious diseases with significant morbidity and mortality. Immunization by the diphtheria and tetanus toxoid (DT) has been applied in Iran for almost 50 years. However, there are very few data about the rate of immunity to these diseases in the adult population. the humoral immunity to tetanus and diphtheria among bloo...

Journal: :Cellular immunology 1974
L T Cahill E Ainbender P R Glade

Routine immunologic screening of four patients with chronic mucocutaneous candi­ diasis (CMC) revealed that they manifested positive Schick tests in ·ui;,o despite adequate diphtheria toxoid immunization and the presence of circulating hemaggluti­ nating antibody to diphtheria. Plasma from these individuals was found to neutralize Schick toxin in rabbits. Unlike normal individuals who preferent...

2015
Colin J. Worby Cynthia Kenyon Ruth Lynfield Marc Lipsitch Edward Goldstein

There is limited information on the roles of different age groups during pertussis outbreaks. Little is known about vaccine effectiveness against pertussis infection (both clinically apparent and subclinical), which is different from effectiveness against reportable pertussis disease, with the former influencing the impact of vaccination on pertussis transmission in the community. For the 2012 ...

2011
Kyong Min Choi Kyung Hyo Kim Yae-Jean Kim Jong-Hyun Kim Su Eun Park Hoan Jong Lee Byung Wook Eun Dae Sun Jo Eun Hwa Choi Young Jin Hong

Pertussis is an acute respiratory infection characterized by paroxysmal cough and inspiratory whoop for over 2 weeks. The incidence of pertussis has decreased markedly after the introduction of DTwP/DTaP vaccine, but the incidence of pertussis has increased steadily among young infant and among adolescents and adults in many countries. Td vaccine was used in this age group but the increase in p...

Journal: :American Journal of Public Health and the Nations Health 1937

2005
Robert C George

© 2005 The Medicine Publishing Company Ltd 31 MEDICINE 33:7 Diphtheria is caused by superficial infection of the respiratory tract or skin with toxin-producing strains of the bacterium Corynebacterium diphtheriae. The organisms do not actively invade deep tissue or the blood, but multiply locally, producing diphtheria toxin. This results in necrosis of the mucosal cells and production of a thic...

2016
Mohamed Tashani Harunor Rashid Kim Mulholland Robert Booy

Pneumococcal conjugate vaccine (PCV) has the potential to interact with other vaccines containing diphtheria toxin-like antigens (such as those found in the DTP vaccine) upon sequential administration. This is attributed to the similarity of the diphtheria toxoid antigen to the carrier protein used to make PCV, (known as cross reactive material [CRM]) to diphtheria toxin 197 or CRM197. The inte...

2006
Frédérique Gouriet Jean-Marc Rolain Didier Raoult

and Wales from 1993 to 2000, an estimated 2–10 secondary cases would have been prevented if attack rates were 5% and each patient had 4 contacts. The number of index cases needed to be detected to prevent 1 death (assuming 6%–10% case-fatality ratio) would have been 150–180 with attack rates of 5% and 50–83 with attack rates of 30%. Thus, deaths were not likely to have been prevented during thi...

2015
Akira Yano Kaori Ito Yoshikatsu Miwa Yoshito Kanazawa Akiko Chiba Yutaka Iigo Yoshinori Kashimoto Akira Kanda Shinji Murata Mitsuhiro Makino

The reduction of brain amyloid beta (Aβ) peptides by anti-Aβ antibodies is one of the possible therapies for Alzheimer's disease. We previously reported that the Aβ peptide vaccine including the T-cell epitope of diphtheria-tetanus combined toxoid (DT) induced anti-Aβ antibodies, and the prior immunization with conventional DT vaccine enhanced the immunogenicity of the peptide. Cynomolgus monke...

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