There is limited evidence comparing the effects of manual and instrumented-assisted manipulations among adults with neck pain. Our purpose was to determine a multisession regime instrument-assisted cervical manipulation on pain, disability, perception change, muscle properties in subjects nonspecific We conducted double-blind, randomized, placebo-controlled study 32 Two groups received three se...

OBJECTIVE To examine the reliability and validity of the physical activity decline (PAD) score: a measure for assessing a decline in the level of physical activity in patients with chronic pain. DESIGN This study was embedded in a prognostic cohort study based on an inception cohort of patients with sub-acute low back pain. PATIENTS Sixty-two patients who developed chronic pain participated...

BACKGROUND AND PURPOSE Health-related quality of life (HRQoL) data are scarce from unselected populations. The aims were to assess HRQoL at 2 years poststroke, to identify determinants of HRQoL in stroke survivors, and to identify predictors at stroke onset of subsequent HRQoL. METHODS All first-ever cases of stroke in a population of 306 631 over a 1-year period were assessed. Stroke severit...

Background. For a long time it has been accepted that the main problem in the anterior knee pain (AKP) patient is in the patella. Currently, literature supports the link between abnormal hip function and AKP. Objective. Our objective is to investigate if Cam femoroacetabular impingement (FAI) resolution is related to the outcome in pain and disability in patients with chronic AKP recalcitrant t...

BACKGROUND Hand-arm vibration syndrome (HAVS) is a well-known disease among workers using hand-held vibrating tools. These patients experience major symptoms from their upper limbs. However, there are few studies on disability in this patient group. In this study we wanted to describe the disability of HAVS patients. METHODS All HAVS patients diagnosed at Haukeland University Hospital in Berg...

Background and Purpose—Health-related quality of life (HRQoL) data are scarce from unselected populations. The aims were to assess HRQoL at 2 years poststroke, to identify determinants of HRQoL in stroke survivors, and to identify predictors at stroke onset of subsequent HRQoL. Methods—All first-ever cases of stroke in a population of 306 631 over a 1-year period were assessed. Stroke severity,...

UNLABELLED OBJECTIVES Our objective was to assess the dynamic serum growth hormone (GH) response to clonidine administration in multiple sclerosis patients, looking for a possible biomarker of degenerative process and to correlative with disability. METHODS 21 patients with relapsing remitting multiple sclerosis, who were evaluated clinically by expanded disability status scale (EDSS) scor...

BACKGROUND Gastroesophageal reflux disease (GERD) causes a wide range of clinical symptoms and potentially serious complications, but epidemiological data about GERD in China are limited. The aim of this pilot study was to develop and validate a methodology for the epidemiological study of GERD in China. METHODS Regionally stratified, randomized samples of Shanghai residents (n = 919) complet...

Given the high opportunity cost of patenting in countries with weak intellectual property right (IPR) protection, it is paradoxical to observe an increase of patenting activities by multinational corporations and indigenous companies in some of those countries in the past decade. We undertake a large-scale firm-level study in the context of China (an emerging economy with weak IPR protection) t...

CONTEXT Interferon beta is widely prescribed to treat multiple sclerosis (MS); however, its relationship with disability progression has yet to be established. OBJECTIVE To investigate the association between interferon beta exposure and disability progression in patients with relapsing-remitting MS. DESIGN, SETTING, AND PATIENTS Retrospective cohort study based on prospectively collected d...