abstract   background: chronic obstructive pulmonary disease (copd) is a major cause of morbidity and mortality, and is an important health economic problem. since 1960, there has been an increase in mortality associated with copd, especially in men. acute exacerbations form a major component of the socioeconomic burden of copd which mainly results in long-term hospitalization. despite the high...

Background: Cardiac involvement was the major leading cause of death in patients with Kawasaki and IVIG administration reduces cardiac complications. The objective of this study was to determine the frequency of cardiovascular complications and duration of fever with regard to the time of intravenous immunoglobulin (IVIG) administration of patients with Kawasaki disease. Methods: This follow...

Results. The selfassessed symptoms of the Dutch FMS patients seem to be valid and are comparable with those of American patients. No association between disease duration and number of self-reported symptoms was found. An association between self-reported pain and mean tender point score was lacking for patients with disease of shorter duration and was weak for patients with disease of longer du...

BACKGROUND AND AIMS We examined the impact of disease duration on clinical outcomes and safety in a post hoc analysis of a remission maintenance trial with adalimumab in patients with moderate to severe CD. METHODS Patients in the CHARM trial were divided into 3 disease duration categories: <2 (n=93), 2 to <5 (n=148), and ≥5 years (n=536). Clinical remission and response rates at weeks 26 and...

abstract background prolonged p-wave duration and p-wave dispersion indicate interatrial conduction disturbance and early predict arrhythmia especially atrial fibrillation. iron deposition in the atrial tissue might prolonged the atrial conduction time, and this study evaluated the p-wave prolongation and increased p-wave dispersion in these patients. materials and methods fifty patients with m...