Background: In COVID-19 pandemic, the diagnosis and treatment must be as early possible to save life of each patient. Moreover, screening asymptomatic carriers, close contacts or healthy subjects not delay prevent transmission publics. For confirmation SARS-CoV-2 infection, nasopharyngeal swab tested either by real-time Reverse Transcription Polymerase Chain Reaction (RT-PCR) tests Rapid Antige...

introduction: although aging is the most important risk factor for alzheimer's disease (ad), there is evidence indicating that neuroinflammation may contribute to the development and progression of the disease. several studies indicated that minocycline may exert neuroprotective effects in rodent models of neurodegenerative diseases. nevertheless, there are also other studies implying that...

We have shown that buspirone, a partial agonist of 5-hydroxytryptamine 1A (5-HT1A) receptors, improves motor dysfunctions induced by 6-hydroxydopamine (6-OHDA) and haloperidol in rats. The present work extends these findings by investigating the role of 5-HT1A receptors on catalepsy-like immobilization in rats, a model of Parkinson’s disease. Catalepsy was induced by unilateral infusion of 6-OH...

Technologies to visualize whole organs across scales in vivo are essential for our understanding of biology health and disease. To date, only post-mortem techniques achieve cellular resolution entire organs. Here, we demonstrate volumetric ultrasound localization microscopy (ULM). We detail a universal methodological pipeline including dedicated 3D ULM, motion correction realignment algorithms,...