In eight patients with exercise-induced asthma, disodium cromoglycate was found to produce a definite inhibition of the post-exercise fall in forced expiratory volume in one second. This effect may be part of the cause for the subjective improvement experienced with this drug.

Abbreviations: DSCG: Disodium Cromoglycate; BPT: Bronchial Provocation Test; SPT: Skin Prick Test; BU: Biologic Unit; FVC: Forced Vital Capacity; FEV1: Forced Expiratory Value in 1 Second; IAR: Immediate (Early) Asthmatic Response; LAR: Late Asthmatic Response; DLAR: Dual Late Asthmatic Response (a combination of IAR and LAR); DYAR: Delayed Asthmatic Response; DDYAR: Dual Delayed Asthmatic Resp...

Introduction: Perchlorate reducing bacteria may serve as model organisms for potential life forms that could exist on Mars. Due to the high reduction potential of perchlorate it can be utilized in microbial metabolism as an electron acceptor [1]. Perchlorate was discovered to be present in martain surface materials (~0.5% wt.) using the Wet Chemistry Laboratory and the Thermal and Evolved Gas A...

CLC-K chloride channels are expressed in the kidney, where they play a pivotal role in the mechanisms of urine concentration and Na(+) reabsorption. The identification of barttin as an essential beta-subunit of CLC-K channels allowed performance of a pharmacologic characterization of wild-type CLC-K1 expressed in Xenopus oocytes. To this end, a series of 2-(p-chlorophenoxy)propionic acid (CPP) ...