This paper provides an historical perspective regarding the role of dissociation in the development of both etiologic theory and treatment paradigms for schizophrenia. References to the concept of dissociation are drawn from classic writings on dementia praecox, and from Bleuler's (1911) original conception of schizophrenia as a splitting" of the personality. An accurate diagnostic distinction ...

Nonclinical studies found that dissociative experiences are intimately linked to a trait known as fantasy proneness. We examined the links among dissociative symptoms, fantasy proneness, and impulsivity in psychiatric outpatients. Our sample consisted of 22 patients with schizophrenia, 20 patients with a diagnosis of borderline personality disorder, and 19 patients with a major depressive disor...

An instrument for the measurement of absolute dissociative electron attachment cross sections was constructed and applied to two prototype molecules, acetylene (C2H2) and deuterated acetylene (C2D2). The isotope effect at the first dissociative electron attachment band at 3 eV was determined--the cross section for C2D-/C2D2 is 14.4 times smaller than that for C2H-/C2H2. The results play a centr...

Although dissociation by definition affects cognition, few studies have used neuropsychological measures to examine dissociative phenomena. This study compared 33 high and 32 low dissociators based on the Dissociative Experiences Scale, on self-report and neuropsychological measures of executive function, including the Dysexecutive Questionnaire, Iowa Gambling Task, Operation Span task, and Wis...

An extensive cross section database for the electron-impact inelastic processes of vibrationally excited molecules of hydrogen and its isotopes is presented. The following inelastic processes are covered: electronic excitation (dissociative and nondissociative), direct ionization (dissociative and nondissociative), excitationradiative decay vibrational excitation and dissociation, and dissociat...

OBJECTIVE This study relates trauma-induced dissociative amnesia reported in World War I (WW I) studies of war trauma to contemporary findings of dissociative amnesia in victims of childhood sexual abuse. METHOD Key diagnostic studies of post-traumatic amnesia in WW I combatants are surveyed. These cover phenomenology and the psychological dynamics of dissociation vis-à-vis repression. RESU...

Background: We sought to determine hippocampal volumes in a sample of inpatients in a Trauma Program specializing in posttraumatic stress disorder and dissociative disorders. Methods: We measured whole brain and left and right hippocampal volumes on MRI in a sample of 20 inpatients in a Trauma Program and 20 controls. Results: There were no differences between the two groups. Nineteen inpatient...

The psychological literature reveals a comorbidity between dissociative and obsessive-compulsive disorders. The exact nature ofthis relationship, however, remains unknown (Steinberg, 1993). This paper offers one explanation by linking the manifestation of dissociative and obsessive-compulsive symptoms to rigidity in the spontaneous organiwtion and integration of cognitive/perceptual experience....

Human ubiquitous mitochondrial creatine kinase (uMtCK) is responsible for the regulation of cellular energy metabolism. To investigate the phosphoryl-transfer mechanism catalyzed by human uMtCK, in this work, molecular dynamic simulations of uMtCK∙ATP-Mg2+∙creatine complex and quantum mechanism calculations were performed to make clear the puzzle. The theoretical studies hereof revealed that hu...

The activation parameters and the rate constants of the water-exchange reactions of Mn(III)TE-2-PyP(5+) (meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin) as cationic, Mn(III)TnHex-2-PyP(5+) (meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin) as sterically shielded cationic, and Mn(III)TSPP(3-) (meso-tetrakis(4-sulfonatophenyl)porphyrin) as anionic manganese(iii) porphyrins were determined from th...