Opioids are among the oldest therapies in our armamentarium, and clinicians recognize their universal utility to limit human distress from pain. Opioids enjoy widespread use as potent analgesics, even though they are abused because of their psychoactive properties. Although the therapeutic and toxic doses are difficult to predict because of the development of tolerance with chronic use, the pri...

OBJECTIVE We examined whether psychological distress predicts incident type 2 diabetes and if the association differs between populations at higher or lower risk of type 2 diabetes. RESEARCH DESIGN AND METHODS This was a prospective cohort of 5,932 diabetes-free adults (4,189 men and 1,743 women, mean age 54.6 years) with three 5-year data cycles (1991-2009): a total of 13,207 person-observat...

While current literature evidences a strong association between gender-based violence exposure and adverse mental health outcomes, few studies have explored how attitudinal acceptance of intimate partner (IPV) might impact this relationship. This analysis employed data from 13–24-year-old females as part the Violence Against Children Surveys in Nigeria, Uganda, Malawi. Mental status, defined by...

background: using of natural and synthetic surfactant is a rescue treatment for respiratory distress syndrome. in iran, survanta and curosurf are the most frequent used natural surfactant preparations. we compared the clinical response and safety of two surfactants poractant alpha (curosurf) and beractant (survanta) for treatment of respiratory distress syndrome (rds) in preterm infants. method...