A 40-year-old woman presented with an asymptomatic red to brown colored walnut-sized, dome shaped, hemorrhagic, crusted nodule on the left forearm. There was no previous history of trauma to the area. The first impression of this case was a vascular tumor or malignant lesion due to the large size and bleeding tendency. However, the final diagnosis, according to histologic and immunostaining met...

It has been shown that the maxillary palps of Locusta migratoria (L.) play an important part in food selection when the insect has not been deprived of food for a long period (Blaney & Chapman, 1970; Blaney, Chapman & Wilson, 1973). The receptors primarily concerned are those on the flexible dome at the distal tip of the palp, and in the fifth instar larvae of Locusta there are about 370 of the...

A 12-year old boy presented with a 2 months history of an itchy eruption over the extremities. The patient complained of a cyclic course with exacerbation in winter. There was no history of asthma, rhinitis or atopic dermatitis. Examination revealed grouped follicular papules forming discoid patches (Fig 1) predominantly over the extensor aspect of forearms and legs. The papules were skin color...

Cherry angiomas are a common cutaneous vascular proliferation which manifests as single or multiple spots and occurs predominantly on the upper trunk and arms. They typically appear as round-to-oval, bright, red, dome-shaped papules and pinpoint macules measuring up to several millimeters in diameter. The histopathologic findings of a cherry angioma are consistent with a true capillary hemangio...

Clear cell acanthoma (CCA) is a rare benign epidermal tumor. It usually presents as a flat nodule or dome-shaped plaque and is often localized on the legs of the elderly. We observed an unusual case of polypoid CCA on the nipple of a 14-year-old girl. At present, a few cases of CCA on the nipple area have been reported in the literature. However, CCA presented as a polypoid tumor on the nipple ...

This paper describes a human blinking eye-on-a-chip microdevice that reconstitutes the ocular surface in the human eye. To recapitulate the structural complexity of the ocular surface, we micro-patterned human cells derived from the cornea and conjunctiva on dome-shaped three-dimensional (3D) scaffolds in in vivo-like spatial arrangements. Moreover, this system was integrated with electromechan...

An 18-year-old Japanese male presented with a normal-skin-colored, dome-shaped, slightly tender tumor on his left palm. Histopathologically, the tumor consisted of distinct lobules, which were separated by fibrous connective tissue. Each lobule was composed of spindle or round cells within a myxoid matrix, pathognomonic of nerve sheath myxoma. The mucinous material was positively stained by Alc...

The different mechanisms involved in the alloying of epitaxial nanocrystals are reported in this Letter. Intermixing during growth, surface diffusion, and intraisland diffusion were investigated by varying the growth conditions and annealing environments during chemical vapor deposition. The relative importance of each mechanism was evaluated in determining a particular composition profile for ...

A healthy 2-year-old girl presented with a rash on her shoulder of 6 months’ duration. Physical examination revealed a solitary 5 mm erythematous dome-shaped papule surrounded by numerous smaller similar lesions (Figure 1). Dermatoscopy visualized numerous central white and skincolored clods with vessels arranged radially to the clods (Figure 2). What is your diagnosis? Please send your answer ...

Perifollicular fibroma (PFF) is a very rare proliferative lesion of the perifollicular sheath. A flesh-colored, dome-shaped papulonodule is usually located on the face or the neck. These papulonodules may be single or multiple. Histologically, the lesion consists of a concentric arrangement of cellular fibrous tissue around a normal hair follicle. We describe here an unusual case of PFF in a 41...