PURPOSE To evaluate donor demographics, trends in donor tissue procurement and tissue storage over a long period. METHODS A retrospective, longitudinal, descriptive analysis was undertaken of data from the Hamburg Eye Bank Data Base (HEB-DB) that had been collected between 1981 and 2010. Data on 54 parameters of cornea donors [including clinical history, age, death cause, gender and death-to-...

CONTEXT Mutations of the fragile X mental retardation 1 (FMR1) gene are associated with distinct ovarian aging patterns. OBJECTIVE To confirm in human in vitro fertilization (IVF) that FMR1 affects outcomes, and to determine whether this reflects differences in ovarian aging between FMR1 mutations, egg/embryo quality or an effect on implantation. DESIGN, SETTING, PATIENTS IVF outcomes were ...

Organ transplantation presents a low but extant risk of allograft transmission of bloodborne viruses (BBV) including human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). Other infections temporarily present in blood are also transmissible from donor to recipient, such as cytomegalovirus (CMV), polyoma‐ virus (BK), Epstein-Barr virus (EBV), and others, where ...

.co m) . donor corneas that were screened in our study. In conjunction with the established quality control for corneal storage in eye banks, there is potential for these PCR assays to aid in rapid screening of clinical specimens for microsporidial contamination and in the diagnosis of ocular infections. Possible causes of primary graft failure could include poor surgical technique, poor donor ...

Multiple birth, which is associated with adverse fetal, infant, and maternal outcomes, is increasingly related to the use of in vitro fertilization (IVF). Among women undergoing IVF who use their own eggs, greater maternal age is associated with decreased risk of multiple birth; using donor eggs from younger women may negate this age effect. Data from 6,936 IVF procedures performed in the Unite...

PRINCIPLES Various non-specific questionnaires were used to measure quality of life and psychological wellbeing of patients after organ transplantation. At present cross-organ studies dealing specifically with the psychological response to a transplanted organ are non-existent in German-speaking countries. METHODS The Transplant Effects Questionnaire TxEQ-D and the SF-36 Quality of Life Quest...