نتایج جستجو برای: donor selection

تعداد نتایج: 382326  

Journal: :Journal of Immunology 2023

Abstract The end result of solid organ transplantation is dictated by selection a well-matched donor, leading to allograft survival. An allogeneic immune response the main immunological barrier for successful transplantation. Donor and recipient human leukocyte antigen (HLA) mismatching results in poor graft acceptance, inflammation rejection. current evaluations donor-recipient HLA incompatibi...

Journal: :The Journal of Heart and Lung Transplantation 2020

Journal: :Seminars in hematology 2016
Shannon R McCurdy Ephraim J Fuchs

The substantial evidence of the safety of human leukocyte antigen (HLA)-haploidentical (haplo) blood or marrow transplantation (BMT) has led to its increasing utilization. When prioritizing HLA-matched grafts, patients frequently have few or no donors from whom to choose. However, a given patient may have multiple suitable haplo donors. Therefore factors other than HLA-match become critical for...

Journal: :Journal of reconstructive microsurgery 2015
Mukta D Agrawal Nanda Deepa Thimmappa Julie V Vasile Joshua L Levine Robert J Allen David T Greenspun Christina Y Ahn Constance M Chen Sandeep S Hedgire Martin R Prince

BACKGROUND Selection of a vascular pedicle for autologous breast reconstruction is time consuming and depends on visual evaluation during the surgery. Preoperative imaging of donor site for mapping the perforator artery anatomy greatly improves the efficiency of perforator selection and significantly reduces the operative time. In this article, we present our experience with magnetic resonance ...

Journal: :Annals of the Academy of Medicine, Singapore 2009
Kelvin K Ng Chung Mau Lo

With the technical advances and improvements in perioperative management and immunosuppressants, liver transplantation is the standard treatment for patients with end-stage liver diseases. In Asia, a shortage of deceased donor liver grafts is the universal problem to be faced with in all transplant centres. Many surgical innovations are then driven to counteract this problem. This review focuse...

Journal: :OBM transplantation 2023

Few reports have described successful lung transplantation from a donor with history of SARS-CoV-2 infection, and outcomes beyond 3 to 6 months remain unknown. After weighing the urgency life-saving benefits against risk viral transmission, we successfully performed bilateral transplant confirmed infection mild symptoms 2 before donation. At 1 year after transplant, there is no evidence donor-d...

2013
Lucas Eduardo Ritacco German Luis Farfalli Federico Edgardo Milano Miguel Angel Ayerza Domingo Luis Muscolo Luis Aponte-Tinao

Structural bone allograft has been used in bone defect reconstruction during the last fifty years with acceptable results. However, allograft selection methods were based on 2-dimensional templates using X-rays. Thanks to preoperative planning platforms, three-dimensional (3D) CT-derived bone models were used to define size and shape comparison between host and donor. The purpose of this study ...

Journal: :Blood 2004
Neal Flomenberg Lee Ann Baxter-Lowe Dennis Confer Marcelo Fernandez-Vina Alexandra Filipovich Mary Horowitz Carolyn Hurley Craig Kollman Claudio Anasetti Harriet Noreen Ann Begovich William Hildebrand Effie Petersdorf Barbara Schmeckpeper Michelle Setterholm Elizabeth Trachtenberg Thomas Williams Edmond Yunis Daniel Weisdorf

Outcome of unrelated donor marrow transplantation is influenced by donor-recipient matching for HLA. Prior studies assessing the effects of mismatches at specific HLA loci have yielded conflicting results. The importance of high-resolution matching for all HLA loci has also not been established. We therefore examined the effects of HLA matching (low or high resolution or both) on engraftment, g...

2016
Zuzana Berkova Frantisek Saudek Peter Girman Klara Zacharovova Jan Kriz Eva Fabryova Ivan Leontovyc Tomas Koblas Lucie Kosinova Tomas Neskudla Ema Vavrova David Habart Sarka Loukotova Martina Zahradnicka Kvetoslav Lipar Ludek Voska Jelena Skibova

Variability of pancreatic donors may significantly impact the success of islet isolation. The aim of this study was to evaluate donor factors associated with isolation failure and to investigate whether immunohistology could contribute to organ selection. Donor characteristics were evaluated for both successful (n = 61) and failed (n = 98) islet isolations. Samples of donor pancreatic tissue (n...

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