Currently, the use of blood irradiation for inactivating pathogenic microbes in infected blood products and preventing graft-versus-host disease (GVHD) in immune suppressed patients is greater than ever before. In these systems, dose distribution and uniformity are two important concepts that should be checked. In this study, dosimetry of the gamma chamber blood irradiator model Gammacell 3000 ...

background: the heterogeneous composition of the human body presents numerous tissue types and cavities with widely differing radiologic properties. the aim of the present work was to develop a low cost homogeneous and heterogeneous phantom and the absorbed dose were measured by ionization chamber for different radiotherapy treatment techniques and compared with treatment planning system absorb...

A patient specific quality assurance program has been developed to facilitate the clinical implementation of intensity modulated radiotherapy (IMRT) delivered using a micro-multileaf collimator. The methodology includes several dosimetric tasks that are performed prior to the treatment of each patient. Film dosimetry is performed for each individual field and for the multifield composite plan. ...

background: in radiation therapy, water is the phantom material of choice, both for reference and for relative dosimetry measurements. solid phantoms, however, are more useful for routine measurements because they tend to be more robust and easier to set up than water phantoms. materials and methods: fluka input data cards have been arranged in sequential order. a simple cylindrical geometry wi...

PURPOSE To design an anthropomorphic pediatric spine phantom for use in the evaluation of proton therapy facilities for clinical trial participation by the Imaging and Radiation Oncology Core (IROC) Houston QA Center (formerly RPC). METHODS This phantom was designed to perform an end-to-end audit of the proton spine treatment process, including simulation, dose calculation by the treatment pl...

An approximate correction method for the CT value-electron density curve of CBCT was established, through comparison and fitting with FBCT images, and applied to evaluate the therapeutic dose of IMRT. The precision of using CBCT for plan calculation was validated by comparing the dose distribution between CBCT- and FBCT-based IMRT plans. Also setup deviations were simulated to evaluate the abil...

A regularized algorithm is presented for localized in vivo shimming. The technique uses first- (X,Y,Z), second- (Z(2), ZX, ZY, X(2)-Y(2), XY), and third-order (Z(3)) shim coils, and is robust when applied to arbitrarily-shaped, as well as off-center, regions of interest (ROIs). A single-shot spiral pulse sequence is used for rapid field map acquisition, and a least-squares calculation of the sh...

background: accurate voxel phantom is needed for dosimetric simulation in radiation therapy for malignant tumors in female pelvic region. however, most of the existing voxel phantoms are constructed on the basis of caucasian or non-chinese population. materials and methods: a computational framework for constructing female pelvic voxel phantom for radiation dosimetry was performed based on chin...

This study details a method to evaluate the source size selection for small field intracranial stereotactic radiosurgery (SRS) deliveries in Eclipse treatment planning system (TPS) for AcurosXB dose calculation algorithm. Our method uses end-to-end dosimetric data to evaluate a total of five source size selections (0.50 mm, 0.75 mm, 1.00 mm, 1.25 mm, and 1.50 mm). The dosimetric leaf gap (DLG) ...

Introduction In computed tomography (CT) technology, an optimal radiation dose can be achieved via changing radiation parameters such as mA, pitch factor, rotation time and tube voltage (kVp) for diagnostic images. Materials and Methods In this study, the brain, abdomen, and thorax scaning was performed using Toshiba 16-slice scannerand standard AAPM and CTDI phantoms. AAPM phantom was used for...