Advances of radiation delivery devices have increased the complexity oncology treatments. Herewith, outcome treatment, as well patient safety, strongly depend on consistency absorbed dose delivery. Both can be ensured by comprehensive system verification calculated distributions. Standard method is evaluation distribution according to gamma method, using a 2-D detector and homogeneous phantom, ...

Background: The success of radiation therapy depends on accurate dose delivery to the target. Diode in vivo measurement of entrance and exit dose is a valuable quality assurance (QA) tool to ensure accurate dose delivery.  Materials and Methods: This study was performed at BINO Cancer Hospital, Bahawalpur. Entrance and exit dose measurements were done with p-type diode for various types of canc...

The purpose of this study was to assess the accuracy and efficacy of an automated treatment plan verification, or "secondary check", tool (Mobius3D), which uses a reference dataset to perform an independent three-dimensional dose verification of the treatment planning system (TPS) dose calculation and assesses plan quality by comparing dose-volume histograms to reference benchmarks. The accurac...

The head and neck is a challenging anatomic site for intensity-modulated radiation therapy (IMRT), requiring thorough testing of planning and treatment delivery systems. Ideally, the phantoms used should be anatomically realistic, have radiologic properties identical to those of the tissues concerned, and allow for the use of a variety of devices to verify dose and dose distribution in any targ...

PURPOSE In the presence of random uncertainties, delivered radiation treatment doses in patient likely exhibit a statistical distribution. The expected dose and variance of this distribution are unknown and are most likely not equal to the planned value since the current treatment planning systems cannot exactly model and simulate treatment machine. Relevant clinical questions are 1) how to qua...

Background: Radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools and tissue-like developed to date. Among the special features of this type of dosimeters, is be doped with other elements or chemicals which made them appropriate for investigating of dose enhancement with contrast agents, by high atomic number. Material and Methods: In this study...

The potential for medication error is great with chemotherapy agents because of their high toxicity profile, small therapeutic index, and numerous dose-limiting adverse effects. The oncology team involved with chemotherapy treatment planning and administration assumes an active role in preventing such events by obtaining and maintaining competency in dose calculations, having knowledge of dose-...

One of the most important aspects of quality assurance (QA) in radiation therapy is redundancy of patient treatment dose calculation. This work is focused on the patient-specific time and 3D dose treatment plan verification for stereotactic radiosurgery using Leksell Gamma Knife Perfexion (LGK PFX). The virtual model of LGK PFX was developed in MATLAB, based on the physical dimensions provided ...

Implementation of Intensity Modulation Radiotherapy (IMRT) and patient dose verification was carried out with film and I'mariXX using linear accelerator with 120-leaf Millennium dynamic multileaf collimator (dMLC). The basic mechanical and electrical commissioning and quality assurance tests of linear accelerator were carried out. The leaf position accuracy and leaf position repeatability check...

Background: 3DCRT (three-dimensional conformal radiotherapy) and IMRT (intensity-modulated radiotherapy) has provided us with tools to delineate the radiation dose distribution of tumor targets. However, the precision of radiation can be compromised by respiratory motion, which usually limits the geometric and dosimetric accuracy of radiotherapy. The purpose of this study is to evaluate the imp...