نتایج جستجو برای: drug resistance http
تعداد نتایج: 1031107 فیلتر نتایج به سال:
conclusion although all esbl producer gram-negative bacteria were sensitive to imipenem, piperacillin-tazobactam, and colistin, non-esbl isolates showed resistant pattern. interestingly, notable percent of mentioned resistant isolates were sensitive to nitrofurantoin. background resistance in enteric gram-negative bacteria is of a great concern and concise local data are lacking. objectives to ...
background: chemotherapy plays a very important role in the treatment of leukemia but the resistance properties of the lymphoblasts limit the effect of chemotherapy. one of the main mechanisms of resistance to chemotherapy is the increased expression of mdr1 gene. the aim of this study was to explore the effect of resveratrol on the expression of mdr1 gene in leukemic lymphoblast of new cases o...
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Association between ABCB1-T1236C Polymorphism and Drug-Resistant Epilepsy in Iranian Female Patients
Background: One third of epileptic patients are resistant to several anti-epileptic drugs (AED). P-glycoprotein (P-gp) is an efflux transporter encoded by ATP-binding cassette subfamily B member 1 (ABCB1) gene that excludes drugs from the cells and plays a significant role in AEDs resistance. Over-expression of P-gp could be a result of polymorphisms in ABCB1 gene. We studied the association of...
MOTIVATION Human immunodeficiency virus type 1 (HIV-1) evolves in human body, and its exposure to a drug often causes mutations that enhance the resistance against the drug. To design an effective pharmacotherapy for an individual patient, it is important to accurately predict the drug resistance based on genotype data. Notably, the resistance is not just the simple sum of the effects of all mu...
Therapeutic success of anti-HIV therapies is limited by the development of drug resistant viruses. These genetic variants display complex mutational patterns in their pol gene, which codes for protease and reverse transcriptase, the molecular targets of current antiretroviral therapy. Genotypic resistance testing depends on the ability to interpret such sequence data, whereas phenotypic resista...
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