Based on data from the Global Tuberculosis Report 2020, it is known that 1.4 million people died tuberculosis. Indonesia ranked third in world with 845,000 cases. It estimated as many 24,000 cases of drug-resistant tuberculosis each year, Multi Drug Resistant (MDR). An initial survey conducted work area UPT Puskesmas Tanjung Morawa found complete treatment rate for all was 60%. One indicators s...

The food supply, including poultry products, may transmit antimicrobial drug-resistant Escherichia coli to humans. To assess this hypothesis, 931 geographically and temporally matched E. coli isolates from human volunteers (hospital inpatients and healthy vegetarians) and commercial poultry products (conventionally raised or raised without antimicrobial drugs) were tested by PCR for phylogeneti...

OBJECTIVES The aim of this study was to estimate the prevalence and identify the risk factors for the development of drug-resistant Mycobacterium tuberculosis infection in a tertiary care center in Oman. METHODS We performed a cross-sectional review of culture-confirmed tuberculosis (TB) cases diagnosed at Sultan Qaboos University Hospital between August 2006 and March 2015. We compared drug-...

Glioblastoma, the most dangerous and aggressive type of CNS tumor, appears resistant to many chemotherapy drugs. In patient-derived glioma cell lines NULU ZAR, which exhibit drug-resistant phenotypes, we investigated effect combined AE (Aloe-emodin) TMZ (temozolomide) found a significant additive inhibitory on growth promising cytotoxic both compared treatment with single agents. We also examin...

The aim of the present study was to understand seasonal occurrence and diversity species meropenem-resistant bacteria in Gumuncheon river receiving effluents from a pharmaceutical industry Seoul, Korea.Water samples were collected Kyoung-gi province during winter (January), spring (April), summer (August), fall (November) 2018. Water plated triplicate on tryptic soy agar plates containing 16 mg...

Enterococci, as the major cause of nosocomial infections, have been shown to have an increase in drug resistance during the past two decades. TheEntrococcalemergence of Vancomycin-resistant is very important nowadays. The purpose of this study was to determine the drug sensitivity of Enterococcus faecalis and Enterococcus faecium species against Vancomycin, Tetracycline, Gentamicin, Erythromyci...

BACKGROUND With almost 9 million new cases each year, tuberculosis remains one of the most feared diseases on the planet. Led by the STOP-TB Partnership and WHO, recent efforts to combat the disease have made considerable progress in a number of countries. However, the emergence of mutated strains of Mycobacterium tuberculosis that are resistant to the major anti-tuberculosis drugs poses a dead...

The development of antiviral drug resistance is an important problem in the treatment of human immunodeficiency virus type 1 (HIV-1) infection. Potent antiretroviral therapy is currently used for treatment, and typically consists of at least two reverse transcriptase (RT) inhibitors. We have previously reported that both drugs and drug-resistant RT mutants can increase virus mutation frequencie...