In today’s scenario, working overtime on computers or watching television has been increased leading to early age dry eye syndrome. The stress can lead to adverse ocular conditions such as those associated with oxidative and/or free radical damage within the eye. These conditions can evolve a condition, disease, or disorder of the cornea, retina, lens, sclera, anterior segment, or posterior seg...

Dry eye syndrome (DES) is a common problem caused by excessive dryness and other factors affecting the general population which involves inflammatory reactions in the cornea and associated regions of the eye. The severity can range from mildly irritating to much more severe symptoms associated with burning, stinging, itching, frequent blinking, redness, eye pain, others. DES prevalence in the p...

AIM This study was designed to examine whether trehalose could protect corneal epithelial cells in culture from death by desiccation in order to test trehalose as a potential new eye drop for dry eye syndrome. METHODS Human corneal epithelial cells in near confluent culture in wells of a 96 well multidish were preincubated for 15 minutes with 2, 20, 50, 100, or 200 mM trehalose or maltose in ...

PURPOSE To compare the clinical presentation of 231 patients with primary Sjögren's syndrome (pSS) with 89 patients with aqueous-deficient dry eye (keratoconjunctivitis sicca; KCS), to determine those procedures that best differentiate these groups in the eye care clinic. METHODS The records of all patients seen at the University Health Network Sjögren's Syndrome Clinic from October 1992 to J...

Objective To describe the use of subconjuctival administration anti-tumor necrosis factor agent adalimumab for treatment dry eye in patients with Sjögren’s syndrome, and to investigate conjunctival healing. Methods Prospective, nonrandomized, noncomparative interventional case series including consecutive syndrome disease treated subconjunctival adalimumab, who were refractory conventional trea...

PURPOSE The purpose of this study is to assess the effectiveness and tolerability of a dietary supplement with a combination of omega-3 fatty acids and antioxidants on dry eye symptoms caused by chronic instillation of antihypertensive eye drops in patients with glaucoma. PATIENTS AND METHODS A total of 1,255 patients with glaucoma and dry eye symptoms related to antiglaucoma topical medicati...

OBJECTIVES To estimate the cost and patterns of expenditure of dry eye treatment. METHODOLOGY We retrieved data on the type and cost of dry eye treatment in Singapore National Eye Centre from pharmacy and clinic inventory databases over a 2 year period (2008-2009) retrospectively. According to the type of treatment, data were sorted into 7 groups; meibomien gland disease (MGD) treatment, pres...

PURPOSE To report a case of extrusion of a new soft punctum plug with thermoexpansion property (Medennium SmartPLUG). METHODS A soft punctum plug was implanted in a 32-year-old woman with a severe dry eye syndrome in juvenile arthritis. RESULTS One week after implant the plug partially extruded outside the punctum. Despite this adverse event, all subjective dry eye symptoms improved. CONC...

The optical function of the eye critically depends on the presence of an intact precorneal tear film. Abnormalities of the tear film such as those occurring in the dry eye syndrome or in otherwise irritated eyes may interfere with vision. In 30 patients with dry eyes artificial tears were found to produce statistically significant improvement of vision (p less than 0.001) while no significant c...