PURPOSE The purpose of this study was to evaluate the image quality and sensitivity of ultralow radiation dose single-energy computed tomography (CT) with tin filtration for spectral shaping and iterative reconstructions for the detection of pulmonary nodules in a phantom setting. METHODS Single-energy CT was performed using third-generation dual-source CT (SOMATOM Force; 2 × 192 slices) at 7...

OBJECTIVE To investigate the effect of intensive lowering of serum uric acid (SUA) levels by pegloticase on the resolution of tophi in patients with refractory gout. METHODS Descriptive study in patients with refractory gout receiving pegloticase treatment. SUA levels were measured before and after each infusion. Dual-energy CT (DECT) scans were taken from all patients before the first infusi...

Regional brain atrophy is a typical structural symptom of Alzheimer's disease (AD). Magnetic resonance imaging (MRl) scans capture brain structure with high resolution and are often processed with automated segmentation and parcellation algorithm like Freesurfer to generate regional measures, llke cortical volume, cortical thickness and surface area, which are widely used as inputs in classific...

The dual energy CT (DECT) technology has been recently employed in the form of two X-ray sources of different energies to enhance the contrast between adjacent structures. Its use in the cardiac arena has been widely highlighted due to the higher temporal resolution. However, it may also be used in the craniocervical and peripheral vasculature for better differentiation between contrast-enhance...

Learning objectives • Dual-energy CT (DECT) can amply contribute to a more efficient workflow in oncologic imaging. • DECT has the potential to reduce the radiation dose and to replace classical dual-phase protocols. • DECT improves oncologic imaging with improved tumour detection and opens up avenues for tissue differentiation and characterisation. • DECT allows for optimised and repeatable th...

Two materials of different composition can have very similar grey values in an X-ray Computed Tomography (CT). This is because X-ray CT uses polychromatic sources in combination with energy-integrating detectors and the materials have a mass attenuation coefficient that is dependent on composition and photon energy. A distinction between different materials with similar grey values can be made ...