We prove that a (globally) subanalytic function f : X ⊂ Qp → Qp which is locally Lipschitz continuous with some constant C is piecewise (globally on each piece) Lipschitz continuous with possibly some other constant, where the pieces can be taken to be subanalytic. We also prove the analogous result for a subanalytic family of functions fy : Xy ⊂ Qp → Qp depending on p-adic parameters. The stat...

Generally, plasma proteins owe their binding capacity to the presence of aminoacid units which enter into intra- and intermolecular hydrophobic bonding with a diverse range of endo- and exogenous chemical substances. The intermolecular interactions between the hydrophobic areas of drug molecules and those of plasma proteins play an important role in drug-macromolecular complex formation and...

Objectives: The distribution of vivax malaria is uneven in India and Plasmodium vivax is predominant in the North-Western part. Distribution of Duffy blood groups and its prevalence are important for regions where P. vivax predominates, because this molecule on the surface of the red blood cell acts as a receptor for P. vivax. The tribal (aboriginal) and desert area of the state Rajasthan contr...

BACKGROUND Erythrocyte Duffy blood group negativity reaches fixation in African populations where Plasmodium vivax (Pv) is uncommon. While it is known that Duffy-negative individuals are highly resistant to Pv erythrocyte infection, little is known regarding Pv susceptibility among heterozygous carriers of a Duffy-negative allele (+/-). Our limited knowledge of the selective advantages or disad...

The Duffy blood group antigen is the portal of entry of the Plasmodiumvivax malaria parasite into human red blood cells and the receptor for a number of CXC and CC chemokines. We review here epidemiological data and evidence derived from therapeutic or experimental human infections associating P. vivax and the Duffy glycoprotein and laboratory studies indicating that P. vivax uses the Duffy ant...

A short-term in vitro culture system that allows for significant re-invasion of target erythrocytes by Plasmodium vivax was used to study the role of the Duffy blood group antigen as a ligand for merozoite invasion by this human malaria species. Using human Duffy-positive and -negative erythrocytes, various primate erythrocytes, enzymatic modification of erythrocytes, and mAb that defines a new...

Duffy was the first blood group mapped to an autosome (chromosome 1) using cytogenetic studies. Duffy antigens are located on a glycoprotein that can be found on erythrocytes and other cells throughout the body. Fy(a) and Fy(b) are products of their respective alleles (FY*A, FY*B). Fy(x) characterized by weak Fy(b) expression, is a result of an additional mutation in FY*B. The Fy(a-b-) phenotyp...