This study presents a case of pneumatosis cystoides intestinalis affecting the terminal ileum in a 25-year old male patient, discovered accidentally during laparotomy for acute abdomen which was proved to be due to perforated duodenal ulcer, Pneumatosis cystoides intestinalis is characterized by the presence of subserosal or submucosal gas filled cysts in the wall of gastrointestinal tract, thi...

Duodenal ulcer perforation is one of the most commonly encountered condition in emergency surgery. Laparoscopic repair has been reported many cases since first laparoscopic a duodenal year 1990 by Mouret et al. Aim and objectives were to study clinical outcomes terms duration surgery, post operative pain, initiation oral feeds, surgical site infection hospital stay. Over 2 period, 2018-2020, 20...

BACKGROUND There is a high prevalence of gastro-duodenal disease in sub-Saharan Africa. Peptic ulcer disease in dyspeptic patients, 24.5%, was comparable to prevalence of gastro-duodenal disease among symptomatic individuals in developed countries (12 - 25%). Limited data exists regarding its associated risk factors despite accumulating evidence indicating that gastroduodenal disease is common ...

Gas within the portal circulation has been known to be associated with a number of conditions most commonly mesenteric ischemia and necrosis. Systemic venous gas is described with few conditions and is mostly iatrogenic in nature. We describe a case of combined portal and systemic venous gas detected by computed tomography in a patient with perforated duodenal ulcer.

Organ culture was used to compare gastrin and somatostatin release from cultured antral mucosa obtained from duodenal ulcer and non-ulcer (control) subjects. In response to dibutyryl cyclic AMP (DBCAMP) cultured antral mucosal explants from patients with a history of duodenal ulcer released a greater proportion of antral gastrin into the medium than did antral mucosal explants from non-ulcer su...

Gastric perforation (GP) in neonates is a rare entity with high mortality. Although the etiology is not completely understood, it mostly occurs in premature neonates on assisted ventilation. Combination of duodenal atresia and gastric perforation is very rare. We present a case duodenal atresia who developed gastric perforation after operetion for duodenal atresia. Analysis of the patient medic...

BACKGROUND Prostaglandin E which is present abundantly in the gastric mucosa is a powerful inhibitor of gastric acid secretion and a stimulus to gastric mucus production. In addition, prostaglandin E2 inhibits ulcer formation in animals, and the synthetic analogues of prostaglandin E have successfully been used in the treatment of patients with gastric and duodenal ulcer disease. To evaluate th...

Gut perforations during ERCP and stenting or due to migration of stents are very rare complications, with an incidence of well below 2%. Moreover, direct duodenoscope-induced lateral or medial duodenal wall perforation is much less common, accounting for 0.1% of patients who undergo ERCP, but tends to be large and further away from the ampulla. Duodenal perforations from the superior duodenal a...

Gastric metaplasia is one of the factors in duodenal ulcer appearance. The aim of this study was to investigate the frequency of gastric metaplasia and its connection with age, sex, cigarette smoking and H. pylori infection. In the study 216 patients were included. There were 98 patients with duodenal ulcer, 60 with duodenitis, and 58 healthy control subjects. There was no statistically signifi...

Peptic ulcer disease (PUD) in children remains rare and difficult to diagnose before the onset of complications. We report on a case of a 12-month child with perforated duodenal ulcer, association with malaria. The severity of the febrile presentation and the positive laboratory confirmation of malaria delayed the diagnosis of PUD. Surgical intervention was successful and without significant se...