The pedicle is a power nucleus of the vertebra and offers a secure grip of all 3 columns. Pedicle screw instrumentation has advantages of rigid fixation with improved three-dimensional (3D) correction and it is accepted as a reliable method with a high margin of safety. Accurate placement of the pedicle screws is important to reduce possible irreversible complications. Many methods of screw ins...

We recently introduced model-based "physiomarkers" of dynamic cerebral autoregulation and CO2 vasomotor reactivity as an aid for diagnosis of early-stage Alzheimer's disease (AD) [1], where significant impairment of dynamic vasomotor reactivity (DVR) was observed in early-stage AD patients relative to age-matched controls. Milder impairment of DVR was shown in patients with amnestic mild cognit...

PURPOSE Kinetic modelling with metabolite-corrected arterial plasma is considered the gold standard for quantification of [11C]PBR28 binding to the translocator protein (TSPO), since there is no brain region devoid of TSPO that can serve as reference. The high variability in binding observed using this method has motivated the use of simplified ratio-based approaches such as standardised uptake...

Complex regional pain syndrome (CRPS) is characterized by severe and chronic pain, but the pathophysiology of this disease are not clearly understood. The primary aim of our case–control study was to explore neuroinflammation in patients with CRPS using positron emission tomography (PET), with an 18-kDa translocator protein specific radioligand [C]-(R)-PK11195. [C]-(R)-PK11195 PET scans were ac...

In this paper, the compensation of voltage sags and swells using a dynamic restorer (DVR) based on bi-directional AC/AC converter is presented for stabilizing single-phase AC line voltage. The H-bridge with switches without bulk capacitor adopted as power topology proposed system. novel DVR to compensate both sag swell conditions. Additionally, factor closed unity because not required. inner ou...

Multi-level converter topologies are increasingly being used in various applications due to their high power, voltage, and low harmonic levels the output waveforms. These produce different voltage have a highly modular structure. This paper proposes design of dynamic restorer (DVR) based on multilevel topology enhance profile improve power quality network. The DVR is an effective, fast-acting d...