During consolidation process of saturated cohesive soil the soil stiffness increases. Increase of the effective stress due to dissipation of excess pore pressure causes additional stiffness of soil mass. This phenomenon has a very important effect on the behavior of saturated cohesive soils during dynamic loading. In the current investigation the changes in maximum shear modulus. Gmax and dampi...

The interaction of work fluid mechanics with that of the rotary system itself, basically composed of axes, bearings and rotors, is performed by inserting equivalent dynamic coefficients in the mathematical model of the rotor, the latter being obtained by the finite element method. In this paper, the dynamic coefficients of inertia, stiffness and damping of the flat seals analyzed here are evalu...

Extracellular matrices determine cellular fate decisions through the regulation of intracellular force and stress. Previous studies suggest that matrix stiffness and ligand anchorage cause distinct signaling effects. We show herein how defined noncovalent anchorage of adhesion ligands to elastic substrates allows for dissection of intracellular adhesion signaling pathways related to matrix stif...

Tissue and matrix stiffness affect cell properties during morphogenesis, cell growth, differentiation, and migration and are altered in the tissue remodeling following injury and the pathological progression. However, detailed molecular mechanisms underlying alterations of stiffness in vivo are still poorly understood. Recent engineering technologies have developed powerful techniques to charac...

Recent developments in the area of smart structures indicate that variable geometry / stiffness truss network is of fundamental importance in designing smart transformable structures and systems for space applications. This paper presents the conceptual design and dynamic modeling of a cooperative re-configurabel dual-arm robotic structure called Dual-Arm Cam-Lock Manipulator. The Manipulator i...

This article presents an analysis of free vibration of elastically supported Timoshenko beams by using the spectral element method. The governing partial differential equation is elaborated to formulate the spectral stiffness matrix. Effectively, the non classical end boundary conditions of the beam are the primordial task to calibrate the phenomenon of the Timoshenko beam-soil foundation inter...

OBJECTIVE Extensive remodeling of the valve ECM in calcific aortic valve sclerosis alters its mechanical properties, but little is known about the impact of matrix mechanics on the cells within the valve interstitium. In this study, the influence of matrix stiffness in modulating calcification by valve interstitial cells (VICs), and their differentiation to pathological phenotypes was assessed....

The dynamics of the magnetic order parameters of ferromagnet/paramagnet/ferromagnet spin valves and isolated ferromagnets may be very different. We investigate the role of the nonequilibrium spin-current exchange between the ferromagnets in the magnetization precession and switching. We find a ~low-temperature! critical current bias for a uniform current-induced magnetization excitation in spin...

Circulating barrier disruptive agonists bind specific cell membrane receptors and trigger signal transduction pathways leading to the activation of cell contractility and endothelial cell (EC) permeability. Although all cells in tissues including vascular EC are surrounded by compliant extracellular matrix, the impact of matrix stiffness on agonist-induced signaling, cytoskeletal remodeling and...