DEAR EDITOR, The group of reticulate pigmentary disorders includes the rare autosomal dominant Dowling–Degos disease (DDD) and Galli–Galli disease (GGD; OMIM 179850, 615327 and 615696). 1 In light of substantial clinical, histological and mutational overlap between GGD and DDD, they are considered to belong to the same entity. 2,3 Mutations in KRT5 (encoding keratin 5) have been associated with...

A Kaposi varicelliform eruption (KVE) refers to a widespread cutaneous infection with a virus that often causes local vesicular eruptions over a pre-existing skin disease. Pemphigus foliaceus complicated by KVE is rare. We report the case of a 68-year-old Chi-nese woman with pemphigus foliaceus complicated by KVE. A 68-year-old woman was admitted to our hospital with a 14-month history of eryth...

White sponge nevus (WSN) is a rare genetic disease with AD inheritance that mostly diagnosed in oral and dental medical departments as the most obvious clinical sign dyskeratotic hyperplasia form of white spongy plaques mucosa. According to published data from Hungary, 13 patients were at Departments Oral Medicine Conservative Dentistry Semmelweis University, histology detailed ultrastructural ...

Tumoración dolorosa de rápido crecimiento en la región subungueal del primer dedo de la mano derecha Medical History A 51-year-old man presented with a very painful, rapidly growing tumor in the subungual area of the first digit of the right hand. The lesion had first appeared a month earlier. The patient had sustained a crush injury to the same digit 20 years earlier. Physical examination reve...

Case History A 67-year-old Sikh male was diagnosed with pemphigus vulgaris in 1996 when he presented with oral erosions. His disease remained controlled on long-term, low-dose prednisolone therapy. In 2004, he developed a verrucous keratotic plaque over the occipital region of his scalp and it had been gradually enlarging (Fig. 1). Biopsies were performed in 2004 and 2008 and histological featu...

OBJECTIVES Still disease is a rare disorder characterized by seronegative arthralgias/arthritis, spiking fever, and either an evanescent salmon-colored rash or persistent papules and plaques. METHODS We describe the clinical and biopsy findings in 10 patients with the evanescent rash of Still disease. RESULTS Fourteen biopsy specimens were studied from seven women and three men with a mean ...

Squamous cell carcinoma (SCC) is classified in many subtypes or forms; one of them is the acantholytic squamous cell carcinoma, also called pseudoglandular, adenoid, epithelioma dyskeratoticum segregans, or adenoacanthoma. Researching and analyzing nine cases of acantholytic squamous cell carcinoma, we intend to verify if the data provided by the cases studied can be validated by the scientific...

A 60-year-old male patient presented with complaints of persistent red to a brown-colored plaque on his scrotum, with duration of approximately three years. The patient had been treated with oral and topical antifungals for inguinal tinea for several months and after that with topical corticosteroids for eczema for several more months. None of the regimens achieved any therapeutic effect. The h...