End-stage cancer patients frequently receive continuous morphine infusion (CMI) to alleviate the various symptoms associated with cancer progression or adverse events; however, there have been a limited number of studies concerning such patients. We conducted a retrospective analysis of 79 end-stage lung cancer patients who received CMI at the Kyoto University Hospital, Kyoto, Japan between 200...

STUDY OBJECTIVE Dyspnea is the uncomfortable sensation of breathing and is an impairing symptom in a variety of diseases. Like pain, it motivates adaptive behavior to regain homeostasis, and both sensations share various characteristics. Whereas the realization of the multidimensionality of pain was a key contribution to pain research, little is known about a similar multidimensionality in the ...

ABSTRACT This systematic review aimed to demonstrate the effectiveness of inspiratory muscle training (IMT) in people with chronic obstructive pulmonary disease (COPD), analyzing effects IMT on strength and endurance, exercise tolerance reduction dyspnea. A search was carried out PubMed, Cochrane Lilacs databases, from August 2021 February 2023, searching for studies published 2016. The descrip...

In acute heart failure syndrome (AHFS), dyspnea is one of the most common but least understood presenting symptoms for hospitalization. For this reason, dyspnea relief is increasingly becoming a focus in the development of therapies for the treatment of AHFS, and currently stands as an acceptable primary end point for regulatory approval by governmental agencies. This raises the question of how...

OBJECTIVES Dyspnea and palpitation are common features of pregnancy. While several theories have been put forward to explain the etiology of gestational dyspnea and palpitation, there have been few systemic studies of its incidence, severity and time-course in a group of normal women. METHODS We interviewed postpartum women, within 3 days after delivery, about dyspnea and palpitation. Separat...

A woman in her 70s with a history of hypertension, hyperlipidemia, and venous thromboembolismpresented to the hospital with 2months of progressivelyworsening dyspnea onexertion.Hermedical historywas significant for a singleepisodeof lower-extremitydeep venous thrombosis during a prior hospitalization, complicated by multiple subsegmental pulmonary emboli. At that time, she underwent inferior ve...

A 41-year-old man was referred to the outpatient clinic of our respiratory care department presenting with the symptoms of progressive cough, exertional dyspnea and tachycardia. The symptoms had started about 18 months earlier and had worsened continuously during the past year. At presentation the patient complained of dyspnea at the slightest exertion. An external chest radiograph showed shado...

INTRODUCTION The association of chest pain versus dyspnea with demographics, coronary angiographic findings, and outcomes of patients undergoing coronary angiography is unknown. MATERIAL AND METHODS We studied 1,053 patients who had coronary angiography to investigate the association of chest pain versus dyspnea with demographics, coronary angiographic findings, and outcomes. RESULTS Of 1,0...

BACKGROUND Dyspnea may be a presenting symptom in progressive systemic sclerosis (SSc). Respiratory drive (mouth occlusion pressure, MOP, at rest and during CO2 rebreathing, 7% CO2, 93% O2) is a major determinant of dyspnea and may relate to the magnitude of dyspnea. METHODS In a prospective design, MOP at 0.1 sec (P0.1) was measured in 73 SSc patients while breathing room air and during CO2 ...

Background  A case report of acute unilateral hemidiaphragm paralysis and resultant dyspnea due to cervical spondylotic myelopathy (CSM) is described. Case Report  An 82-year-old man presented with a nonproductive cough, chest congestion, hoarseness, and shortness of breath on ambulation. The patient underwent cardiac catheterization, which revealed extensive stenosis of the major cardiac arter...