The text analyzes the contradictions, ambiguities and accommodations underlying the remodelling of Portugal from an imperial metropolis into a European post-colonial nation. It focuses on two interrelated and contradictory facets of national redefinition – namely, the incorporation of Portuguese transnational migrants into the nation and Portugal’s transformation into a receptor of immigrants f...

Abrupt weaning, a usual management in sheep productive systems, may provoke behavioural and physiological responses indicative of stress in ewes and lambs. Progesterone (P4) has anxiolytic and sedative effects through the union of its metabolites that contain 3α-hydroxyl group to the γ-aminobutyricacidA receptor. Our first aim was to determine whether P4 administration reduces the behavioural a...

We perform shell model calculations in odd-odd nuclei using a quadrupolequadrupole interaction with single-particle splittings chosen so as to obtain the SU(3) results. Elliott had shown that such an interaction gives rotational bands for which the energies go as I(I + 1). This certainly is true for eveneven and for odd-even or even-odd nuclei with K 6= 1/2. We have looked at odd-odd nuclei e.g...

The excitation functions of the key reactions of stellar nucleosynthesis, 12C(α, γ)16O and 22Ne(α, n)25Mg, have been determined with an experimental sensitivity of 10−11 barn. For 12C(α, γ)16O the SE1and SE2-factors deduced from the γ angular distributions have been extrapolated into the range of helium burning temperatures applying the R-matrix method, which yielded S300 E1 = (76± 20) keVb and...

Let κ be an inaccessible cardinal, and let E0 = {x ∈ Pκκ : cf λx = cf κx} and E1 = {x ∈ Pκκ : κx is regular and λx = κx }. It is consistent that the set E1 is stationary and that every stationary subset of E0 reflects at almost every a ∈ E1.

Gonadotropin-releasing hormone (GnRH), a neuropeptide released from a small population of neurons in the hypothalamus, is the central mediator of the hypothalamic-pituitary-gonadal axis, and is required for normal reproductive development and function. Evolutionarily conserved regulatory elements in the mouse, rat, and human Gnrh1 gene include three enhancers and the proximal promoter, which co...

CEE (conjugated equine estrogens) is the most widely prescribed estrogen-only menopausal hormone therapy in the United States, and is comprised of over 50% estrone (E1) sulfate. Following CEE administration, E1 is the principal circulating estrogen. However, the cognitive and neurobiological effects of E1 in a middle-aged rodent model have not yet been evaluated. We assessed cognitive effects o...

Abstract Background Genetic testing for inherited arrhythmias and discriminating pathogenic from benign variants are integral the gene-based medicine. However, high throughput in vivo functional analysis rare of KCNQ1 potassium channel is scarce. Purpose We tested utility zebrafish cardiac assay determining pathogenicity identified patients with long QT syndrome (LQTS) atrial fibrillation (AF)....