BACKGROUND Some previous research has suggested that testosterone prenatally contributes to gender differences in autistic traits, but little is known about the role of testosterone during early postnatal development (mini-puberty). Two prior studies found no sex difference in testosterone postnatally in saliva samples and detected little to no relationship between testosterone postnatally and ...

Precocious puberty (PP) is defined as the development of pubertal changes before the accepted age of its onset. In girls the lower limit of puberty is set at8 year.[1] With PP early secondary sexual changes appear. By definition it is presence of signs at Tanner 2 stage. It starts at 8 year of age and continues till 15 year of age. The signs include elevation of breast and its papilla with the ...

Adopted children show more problem behaviors than nonadopted children. Given that internationally-adopted individuals show earlier puberty than non-adopted individuals, and early puberty is associated with problem behaviors in nonadopted youth, we analyzed data from domestic adoptees to determine whether problem behaviors could be explained by differences in pubertal timing. Relative to nonadop...

the present study aimed to evaluate the effects of ramadan fasting on the level of sex hormones in girls between 9-13 years before age at menarche.this study was conducted on a sample of 58 subjects (age range: 9-13 years), who were divided intotwo groups of fasting (n=31) and non-fasting (n=27). the levels of follicle-stimulating hormone(fsh), luteinizing hormone (lh), progesterone and estradi...

Changes in puberty timing have implications for the treatment of individual children, for the risk of later adult disease, and for chemical testing and risk assessment for the population. Children with early puberty are at a risk for accelerated skeletal maturation and short adult height, early sexual debut, potential sexual abuse, and psychosocial difficulties. Altered puberty timing is also o...

OBJECTIVES Idiopathic central precocious puberty and its postponement with a (gonadotropin-releasing hormone) GnRH agonist are complex conditions, the final effects of which on bone mass are difficult to define. We evaluated bone mass, body composition, and bone remodeling in two groups of girls with idiopathic central precocious puberty, namely one group that was assessed at diagnosis and a se...