نتایج جستجو برای: edaravone

تعداد نتایج: 529  

2017
Haiyan Yan Hongyan Xi Hongmei Wang Fengchun Zhang Duanhua Cao

Purpose: This study aims to investigate the effect of butylphthalide on the prognosis of acute massive cerebral infarction (MCI). Methods: A total of 92 MCI patients, who received inpatient treatment in the Department of Neurology, Harrison International Peace Hospital from February 2011 to December 2013, were enrolled into this study. As a controlled study, patients were randomly divided into ...

Journal: :Japanese Journal of Cardiovascular Surgery 2011

Journal: :Revue Neurologique 2021

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by death of motor neurons in the cortex and spinal cord. This loss causes progressive weakness amyotrophy. To date, median duration survival patients with ALS, from first symptoms to death, estimated be 36 months. Currently treatment limited two options: riluzole which prolongs for few months edaravone availa...

Journal: :Investigative ophthalmology & visual science 2011
Hiromi Ogishima Shinsuke Nakamura Tomohiro Nakanishi Shunsuke Imai Mamoru Kakino Fumiya Ishizuka Kazuhiro Tsuruma Masamitsu Shimazawa Hideaki Hara

PURPOSE This study aimed to characterize the functional and morphologic changes in a murine model of ocular ischemic disease caused by vascular occlusion. METHODS Retinal ischemia was induced by unilateral ligation of the pterygopalatine artery (PPA) and the external carotid artery (ECA) in anesthetized mice. Changes in ocular blood flow and retinal circulation were evaluated by three differe...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2016
Rou-Ling Cho Chien-Chung Yang I-Ta Lee Chih-Chung Lin Pei-Ling Chi Li-Der Hsiao Chuen-Mao Yang

Upregulation of intercellular adhesion molecule-1 (ICAM-1) is frequently implicated in lung inflammation. Lipopolysaccharide (LPS) has been shown to play a key role in inflammation via adhesion molecule induction and then causes lung injury. However, the mechanisms underlying LPS-induced ICAM-1 expression in human pulmonary alveolar epithelial cells (HPAEpiCs) remain unclear. We showed that LPS...

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