The work being reported is the first electrochemical sensor for tetrodotoxin (TTX). It was developed on a glassy carbon electrodes (C) that was modified with poly(4-styrenesolfonic acid)-doped polyaniline film (PANI/PSSA). An amine-end functionalized TTX-binding aptamer, 5'-NH₂-AAAAATTTCACACGGGTGCCTCGGCTGTCC-3' (NH₂-Apt), was grafted via covalent glutaraldehyde (glu) cross-linking. The resultin...

Particulate matter (PM) air pollution has a significant impact on human morbidity and mortality; however, the mechanisms of PM-induced toxicity are poorly defined. A leading hypothesis states that airborne PM induces harm by generating reactive oxygen species in and around human tissues, leading to oxidative stress. We report here a system employing a microfluidic electrochemical sensor coupled...

8 ABSTRACT: Particulate matter (PM) air pollution has a 9 significant impact on human morbidity and mortality; 10 however, the mechanisms of PM-induced toxicity are poorly 11 defined. A leading hypothesis states that airborne PM induces 12 harm by generating reactive oxygen species in and around 13 human tissues, leading to oxidative stress. We report here a 14 system employing a microfluidic e...

A novel electrochemical sensor for bovine hemoglobin (BHb) recognition and detection was prepared by a surface molecularly imprinted technique. Aldehyde group-functionalized silica microspheres were modified on an Au electrode surface, and these were subsequently covalently bound with the template molecule, BHb, through imine bonds. Electropolymerization was performed to deposit polypyrrole ont...

Electrochemical microsensors are ideal to measure substances with low concentration in complex environments. The primary excitatory neurotransmitter L-glutamate is present in many foods as a distinctive flavour (enhancer) with a wide concentration range. In comparison to other methods, electrochemical sensors allow the rapid, precise, cost-effective, online measurement without any sample treatm...

Electrochemical sensors for multiple analytes were the first scitifically proposed as well as commersialised biosensors. Electrochemical biosensors have been studied for a long time. Presently, typical platform of transducers based on semiconductors and screen printed electrodes is in practice for construction of biosensors. Among all biocomponents enzymes or enzyme labeled antibodies are prese...

Folic acid (FA) is a water soluble vitamin that exists in many natural species. The lack of FA causes some deficiencies in the human body, so finding a simple and sensitive method for determining the FA is important. One of the modern techniques which overcome the disadvantages of conventional determination methods is the sensors. Possibility of miniaturization, the development of microfabricat...

A simple and sensitive poly(gallic acid)/multiwalled carbon nanotube modified glassy carbon electrode (PGA/MWCNT/GCE) electrochemical sensor was prepared for direct determination of the total phenolic content (TPC) as gallic acid equivalent. The GCE working electrode was electrochemically modified and characterized using scanning electron microscope (SEM), cyclic voltammetry (CV), chronoamperom...

This article presents a novel membrane-based sensor for real-time electrochemical investigations of cellular- or tissue cultures. The membrane sensor enables recording of electrical signals from a cell culture without any signal dilution, thus avoiding loss of sensitivity. Moreover, the porosity of the membrane provides optimal culturing conditions similar to existing culturing techniques allow...