OBJECTIVE: The most common indication for cochlear implantation includes profound/complete sensorineural hearing loss, with no benefit from a hearing aid, due to lesion in the cochlea. STUDY DESIGN: Between January 2003 and December 2005 in the ENT Department of the University of Medicine Timisoara, 24 patients were fitted with cochlear implants. Devices used include: Combi 40+ (14), Pulsar CI ...

Electrocochleography (ECochG) has been used to assess Ménière's disease, a pathology associated with endolymphatic hydrops and low-frequency sensorineural hearing loss. However, the current ECochG techniques are limited for use at high-frequencies only (≥1 kHz) and cannot be used to assess and understand the low-frequency sensorineural hearing loss in ears with Ménière's disease. In the current...

The aim of this study was to use functional and morphological analyses to evaluate the protective effect of coenzyme A (CoA) in cisplatin-induced toxicity in outer hair cells (OHC). Three groups of 8 guinea pigs were used: control (group I), cisplatin-treated (group II) and cisplatin + CoA-treated (group III). In groups II and III, a single ototoxic dose of cisplatin (10 mg/kg) was injected int...

The aim of this paper is to assess the long-term audiological features and outcomes of hearing rehabilitation in a large group of individuals with CHARGE Syndrome. The study has been conducted retrospectively, on a paediatric patient database, at the Audiology Department of the University Hospitals of Ferrara and Padua. The study sample included 31 children presenting with different degrees of ...

With changes to cochlear implant candidacy and improvements in surgical technique, there is a need for accurate intraoperative assessment of low-frequency hearing thresholds during cochlear implantation. In electrocochleography, onset compound action potentials (CAPs) typically allow estimation of auditory threshold for frequencies above 1 kHz, but they are less accurate at lower frequencies. A...

background: meniere’s disease (md) is a chronic illness defined as an idiopathic syndrome of endolymphatic hydrops. benign paroxysmal positional vertigo (bppv) is a balance disorder and can be the sequel of diverse inner ear impairments. objectives: the purpose of this study was to investigate the prevalence of bppv in md patients. materials and methods: all patients with definite or probable m...

Background: Meniere’s disease (MD) is a chronic illness defined as an idiopathic syndrome of endolymphatic hydrops. Benign paroxysmal positional vertigo (BPPV) is a balance disorder and can be the sequel of diverse inner ear impairments. Objectives: The purpose of this study was to investigate the prevalence of BPPV in MD patients. Materials and Methods: All patients with definite or prob...

UNLABELLED Utriculostomy is a new surgical alternative for Ménière's disease. The basis of this procedure is that the outcome of an electrocautery-induced utricular trauma does not affect cochlear function. However, a demonstration of the hypothesis that this approach to the utricle would preserve hearing is still pending. OBJECTIVE To determine whether any changes would occur in the electric...

UNLABELLED Hyperinsulinism secondary to peripheral insulin resistance has been described as the most frequent etiologic factor in cochlear and vestibular syndromes. AIM This experimental study recorded and analyzed evoked auditory potential changes using transtympanic electrocochleography (EcochG) during induced acute hyperinsulinism in an animal model. MATERIALS AND METHODS Six adult male ...