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1 Department of Laboratory Medicine, Beijing Hospital, No.1 DaHua Road, Beijing 100730, China 2 Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences/School of Basic Medicine, Peking Union Medical College, Beijing, China Department of Biochemistry and Molecular Biology, Beijing Normal University, Gene Engineering and Biotechnology Beijing Key La...

We describe a case of acute disseminated encephalomyelitis in a child. This case is unusual in that the illness was characterised by recurrent episodes rather than a monophasic course and that the choice of treatment was intravenous immunoglobulin over corticosteroids. The rapid and remarkable recovery is highlighted and a review of the treatment for this rare condition is discussed.

Introduction Intracranial infections involving the bones of the skull or spine (osteomyelitis), the extradural compartments, the pachymeninges (dura), subdural space, leptomeninges and subarachnoid space are mainly caused by bacteria and occasionally by fungi and viruses (leptomeningitis). The organisms that infect the CNS itself (the brain and the spinal cord) are mainly viruses and bacteria, ...