Exocrine and endocrine pancreatic function was studied in the rat after occlusion of the pancreatic ducts with acrylate or prolamine, respectively. After 5 months the effect of these procedures was a clear-cut exocrine insufficiency as evidenced by reduced enzyme activities in pancreatic tissue and in intestinal content, while the endocrine function was not impaired. The insulin secretory respo...

background: one of the most common endocrine problems in major beta-thalassemia is hypothyroidism (ht). the aim of this study was to evaluate thyroid function status in major beta-thalassemia patients older than 10 years old. methods: this cross sectional study was carried out on thalassemia major patients registered on thalassemia center of amirkola children hospital in babol. a questionnaire ...

Endocrine and exocrine pancreas tissues are both derived from the posterior foregut endoderm, however, the interdependence of these two cell types during their formation is not well understood. In this study, we generated mutant mice, in which the exocrine tissue is hypoplastic, in order to reveal a possible requirement for exocrine pancreas tissue in endocrine development and/or function. Sinc...

ment. An introductory section of this chapter deals with criteria of endocrine function and methods and difficulties encountered in studying endocrine problems. This is a useful part of the book and should be of value to the student. Whereas the first two chapters deal at a general level with the topics of osmoregulation and endocrine control, the following chapters cover the function of these ...

The autonomic nervous system regulates hormone secretion from the endocrine pancreas, the islets of Langerhans, thus impacting glucose metabolism. The parasympathetic and sympathetic nerves innervate the pancreatic islet, but the precise innervation patterns are unknown, particularly in human. Here we demonstrate that the innervation of human islets is different from that of mouse islets and do...

There is growing evidence that male as well as female reproductive function has been declining in human and wildlife populations over the last 40 years. Several factors such as lifestyle or environmental xenobiotics other than genetic factors may play a role in determining adverse effects on reproductive health. Among the environmental xenobiotics phthalates, a family of man-made pollutants are...

During the last 10 to 15 years enormous progress has been made with regard to quality of ultrasound equipment. The improved resolution has enabled consistent visualisation of endocrine glands in dogs and cats and today ultrasonography is routinely used in the workup of endocrine diseases. It is important to remember, that ultrasonographic imaging gives information on size, shape and parenchyma ...

The term endocrine-disrupting chemicals is used to define a structurally diverse class of synthetic and natural compounds that possess the ability to alter various components of the endocrine system and potentially induce adverse health effects in exposed individuals and populations. Research on these compounds has revealed that they use a variety of both nuclear receptor-mediated and non-recep...

The major concerns with endocrine disruptors in the environment are based mostly on effects that have been observed on the developing embryo and fetus. The focus of the present manuscript is on disruption of three hormonal systems: estrogens, androgens, and thyroid hormones. These three hormonal systems have been well characterized with regard to their roles in normal development, and their act...

Background: One of the most common endocrine problems in major beta-thalassemia is hypothyroidism (HT). The aim of this study was to evaluate thyroid function status in major beta-thalassemia patients older than 10 years old. Methods: This cross sectional study was carried out on thalassemia major patients registered on Thalassemia Center of Amirkola Children Hospital in Babol. A questionnaire ...