Eosinophilia is common in childhood, and in most cases it is mild and of limited clinical relevance, being often secondary to allergy or infections. In rare cases, eosinophilia may be idiopathic or related to neoplastic aetiology. When severe and protracted, it can cause potentially irreversible organ or system damage, whose prevention is the first priority in the clinical management of hypereo...

Cross-sectional and longitudinal studies have been carried out to determine the incidence and clinical significance of eosinophilia in patients taking penicillamine for rheumatoid arthritis. In a cross-sectional study of 204 patients eosinophilia was found with equal frequency during treatment with penicillamine, gold, and nonsteroidal anti-inflammatory drugs. A longitudinal study of 89 patient...

A series of four patients with pulmonary infiltrates, pleural effusions, hypoxemia, peripheral eosinophilia, and symptoms of dyspnea, fatigue, and weakness is reported. Lung tissue obtained in three patients revealed interstitial pneumonitis, small-to-medium-vessel mixed-cell vasculitis, and alveolar exudate of histiocytes and eosinophils. All patients reported ingestion of L-tryptophan-contain...

Pulmonary eosinophilia comprises a heterogeneous group of diseases that are defined by eosinophilia in pulmonary infiltrates or in tissue. Drugs can cause almost all histopathologic patterns of interstitial pneumonias, such as cellular and fibrotic nonspecific interstitial pneumonia, pulmonary infiltrates and eosinophilia, organizing pneumonia, lymphocytic interstitial pneumonia, desquamative i...

background: cardiovascular diseases are the most common cause of deaths in iran and other developing countries. the risk factors for cardiovascular diseases are divided into two categories; the variable risk factors and the non-variable risk factors. many recent studies evaluated the relationship between higher eosinophilia and allergy levels with the incidence, progress and severity of cardiov...

Eosinophilic lung diseases comprise eosinophilic pneumonia, which may present with chronic or acute onset, or as Löffler syndrome. The diagnosis of eosinophilic pneumonia relies on clinical imaging and the demonstration of alveolar eosinophilia. Lung biopsy is generally not necessary. Peripheral blood eosinophilia is common but may be absent at presentation in idiopathic acute eosinophilic pneu...

Typical clinical and radiological features of tropical pulmonary eosinophilia were originally described by Weingarten.' Cases of tropical pulmonary eosinophilia were initially recorded in India, but the disease is now known to occur throughout the world. Various atypical radiological presentations such as cavitation,2pleural effusion,3' and patchy pneumonitis5 7 have been reported. Very few cas...

Hypereosinophilic syndromes (HESs) are a heterogeneous group of uncommon disorders characterized by marked peripheral eosinophilia and end organ manifestations attributable to the eosinophilia or unexplained in the clinical setting. Whereas corticosteroids remain the mainstay of treatment for most patients, recent diagnostic advances and the development of novel targeted therapies, including ty...

Angiolymphoid hyperplasia with eosinophilia, also known as epithelioid hemangioma, is a rare endothelioproliferative disorder which clinically presents with reddish to reddish brown, single or multiple, papules and nodules predominantly on head and neck region in middle aged women. Its aetiopathogenesis is still unclear. Histopathologically, it is characterized by proliferation of plump or epit...

Obstructive chronic pancreatitis in children occurs as a result of congenital or acquired stricture of the pancreatic duct. The prominent histologic changes are characterized by periductal fibrosis and subsequent ductal dilatation. Diagnosis is usually made by imaging studies such as endoscopic retrograde cholangiopancreaticography, ultrasonography, and pancreatic function testing. Eosinophilia...