The role of brain-derived neurotrophic factor (BDNF) in sensory hypersensitivity has been suggested; however the molecular mechanisms and signal transduction that regulate BDNF expression in primary afferent neurons during visceral inflammation are not clear. Here we used a rat model of cystitis and found that the mRNA and protein levels of BDNF were increased in the L6 dorsal root ganglia (DRG...

Lupus enteritis and lupus cystitis are relatively rare manifestations of systemic lupus erythematosus. Some patients develop severe complications such as bowel perforation, infarction, obstruction, or irreversible bladder dysfunction. Early diagnosis is critical for management of lupus enteritis and cystitis. We report a 48-year-old Japanese man who presented with initial manifestations of abdo...

Novel longer lasting inflammatory bladder animal models are needed to better understand the pathophysiology of chronic cystitis. We previously developed a relatively long-lasting mouse cystitis model by intravesical injection of hydrogen peroxide (H2O2). To further evaluate its pathophysiology, in this study, we established and analyzed a rat cystitis model. Under anesthesia, 1.5% H2O2 solution...

OBJECTIVE To evaluate how the effect of acupuncture treatment in recurrent cystitis relates to Traditional Chinese Medicine (TCM) diagnostic categories and physiologic measurements. SETTING/LOCATION Two private acupuncture clinics in Bergen, Norway. Measurements were carried out in Haukeland University Hospital, Bergen. DESIGN AND SUBJECTS Ninety-eight (98) cystitis-prone women were randoml...

This study utilized magnetic resonance imaging (MRI) to monitor the real-time status of the urinary bladder in normal and diseased states following cyclophosphamide (CYP)-induced cystitis, and also examined the role of the phosphoinositide 3-kinase (PI3K) pathway in the regulation of urinary bladder hypertrophy in vivo. Our results showed that under MRI visualization the urinary bladder wall wa...

Eosinophilic gastroenteritis is a rarely reported condition. The disease is characterized by peripheral blood eosinophilia, eosinophilic infiltration of the bowel wall to a variable depth, and gastrointestinal complaints. Allergic diathesis can be found in most of the cases. In this article we report two cases with interesting epidemiological characteristics and we will have a brief review ...

Cystitis is an inflammation of the urinary bladder which common in domestic animals as part a tract infection. Clinical symptoms cystitis are lower abdominal pain on palpation, dysuria (animals show signs every attempt to urinate) and hematuria. The diagnosis can be obtained through anamnesis, physical examination, clinical symptoms, urinalysis with sediment blood chemistry examinations such ur...

Objectives: To demonstrate the outcome of transvaginal urethrolysis as a treatment option for women with recurrent cystitis, which could be caused from voiding problems. In case failure non-invasive treatment, surgical procedure to decrease outlet resistance may have role. Materials and Methods: Between January 2016 December 2020, cystitis who underwent at Siriraj Hospital were retrospectively ...

In a randomised, double blind, long term, crossover study 1 g twice daily of methenamine hippurate was compared with placebo for its preventive effect on recurrent attacks of acute cystitis. Methenamine hippurate and placebo were interchanged every six months for two years. During one of the years patients took 250 ml extra fluid every morning and evening. Out of 21 enrolled patients, 14 comple...

The incidence of cystitis is much higher than that of pyelonephritis. Uncomplicated UTIs are episodios of acute cystitis or pyelonephritis when it occurs in a healthy premenopausal, non-pregnant woman with no known urological abnormalities (structural or functional) [1-5]. UTI that do not meet these criteria is considered complicated. This review is focused on management of acute uncomplciated ...