Impaired revascularization of transplanted islets is a critical problem that leads to progressive islet loss. Since endothelial progenitor cells (EPCs) are known to aid neovascularization, we aimed to enhance islet engraftment by cotransplanting EPCs with islets. Porcine islets, with (islet-EPC group) or without (islet-only group) human cord blood-derived EPCs, were transplanted into diabetic n...

Eccrine porocarcinoma (EPC) is a rare type of skin cancer arising from the intraepidermal portion of eccrine sweat glands or acrosyringium, representing 0.005-0.01% of all cutaneous tumors. About 20% of EPC will recur and about 20% will metastasize to regional lymph nodes. There is a mortality rate of 67% in patients with lymph node metastases. Although rare, the occurrence of distant metastase...

Communication between distantly spaced genomic regions is one of the key features of gene regulation in eukaryotes. Chromatin per se can stimulate efficient enhancer-promoter communication (EPC); however, the role of chromatin structure and dynamics in this process remains poorly understood. Here we show that nucleosome spacing and the presence of nucleosome-free DNA regions can modulate chroma...

OBJECTIVES This study was designed to evaluate whether rapid endothelialization of stainless steel stents with a functional endothelium prevents stent thrombosis and reduces the restenotic process. BACKGROUND A "pro-healing" approach for prevention of post-stenting restenosis is theoretically favored over the use of cytotoxic or cytostatic local pharmacologic therapies. It is believed that th...

Liver fibrosis (LF) caused by chronic liver damage has been considered as an irreversible disease. As alternative therapy for liver transplantation, there are high expectations for regenerative medicine of the liver. Bone marrow (BM)- or peripheral blood-derived stem cells, including endothelial progenitor cells (EPCs), have recently been used to treat liver cirrhosis. We investigated the biolo...

INTRODUCTION Erythropoietin (EPO) enhances the circulating level of endothelial progenitor cells (EPCs), which has been reported to be associated with prognostic outcome in ischemic stroke (IS) patients. The aim of this study was to evaluate the time course of circulating EPC level and the impact of EPO therapy on EPC level and clinical outcome in patients after acute IS. METHODS In total, 16...

Neither the European Patent Convention (EPC) nor the Patent Cooperation Treaty (PCT) have touched and influenced in any manner the way in which patents can be presently enforced in the member countries of the European Union (EU) and/or of EPC. This situation, however, would change dramatically if some kind of a Community Patent (CP) would be introduced, the fate of a draft EU Regulation for int...

El artículo presenta un recorrido por algunas discusiones teóricas vinculadas a la forma en que televisión pública enfrenta convergencia digital. Desde perspectiva de Economía Política Comunicación (EPC), el trabajo retoma algunos problemas clásicos y actuales agenda EPC, como concentración comunicacional, economía las plataformas democratización comunicación. Con estas herramientas, busca real...

This analysis compares the difference between Energy Performance Certificate (EPC)-modelled and smart-meter measured annual energy use on a like-for-like basis in 1,374 gas-heated British households from Smart Research Lab (SERL) Observatory. EPCs metered were converted to primary intensity (PEUI) provide comparison of same quantity for first time. We show that predict significantly more than h...

We aimed to examine the relationship between levels of socio-economic disadvantage (measured by the Socio Economic Indexes for Areas [SEIFA] used by the Australian Bureau of Statistics) and uptake of the Enhanced Primary Care (EPC) item numbers on the Medicare Benefits Schedule. Health services are often less likely to reach those that most need them and so it is important to monitor whether di...