During the past several years there has been a growing interest in epidemiologic investigation, particularly in the field of non-infectious diseases. Although a few books devoted to epidemiology are available, for the most part the subject has been presented in public health and preventive medicine textbooks, in which methodology has often taken second place to a descriptive epidemiology of spe...

PURPOSE The aim of this study was to evaluate the prevalence of Benign Vocal Fold Lesion (polyp, cysts, nodules) and Leukoplakia in Korea. MATERIALS AND METHODS The data from the 2008 to 2011 Korea National Health and Nutrition Examination Surveys, which were cross-sectional survey of the civilian noninstitutionalized population of South Korea. A survey team that included an otolaryngology re...

Insulin-like growth factor-I (IGF-I) is abundant in the circulation and has been shown to have a wide array of biologic effects. The authors carried out a cross-sectional community-based study of 420 men and 419 nonestrogen-using postmenopausal women aged 50-97 years to ascertain the within-person and laboratory reliability of IGF-I measurements, and the association of IGF-I with common epidemi...

BACKGROUND Coenzyme Q10 (CoQ10) is considered to be a potential anticancer agent, but epidemiologic evidence regarding CoQ10 and prostate cancer risk is lacking. We examined the association of circulating CoQ10 levels with prostate cancer risk, using prediagnostic blood samples. METHODS Each of the 307 cases was individually matched to approximately 2 controls, for a total of 596 controls, on...

BACKGROUND Despite considerable epidemiologic evidence about the health effects of chronic exposure to vehicle exhaust, efforts at defining the extent of risk have been limited by the lack of historical exposure measurements suitable for use in epidemiologic studies and for risk assessment. OBJECTIVES We sought to reconstruct exposure to elemental carbon (EC), a marker of diesel and other veh...

OBJECTIVE To review the epidemiologic literature on styrene and cancer. METHODS We reviewed studies of workers exposed to styrene in manufacturing and polymerization, in the reinforced plastics industry, and in styrene-butadiene rubber production. We also reviewed studies of workers monitored for styrene exposure, studies of environmental exposure, community-based case-control studies of lymp...

With the implication of dietary factors in the origin of many common diseases, there has been renewed interest in methods of dietary enquiry suitable for epidemiologic research (1-14). Validation of both new and old approaches proceeds, but under severe constraints. In the development of questionnaires, for example, the need may arise to compare two alternative, simple methods each to a referen...

OBJECTIVE to review the extensive literature pertaining to the reproductive and teratogenic effects of Bendectin and the opinions of the scientific experts for the defense and plaintiff. These data were evaluated with regard to the reproductive risks of Bendectin providing a scientific framework for evaluating the views of the experts in the Bendectin litigation. DESIGN the Bendectin literatu...