BACKGROUND AND OBJECTIVES Estimation of GFR in children from serum creatinine measures in regional databases is limited by a lack of height data. Furthermore, the ability of GFR estimating equations to quantify changes in GFR over time is unknown. Two methods of estimating GFR when height is unknown and the ability of several GFR equations to quantify GFR changes over time were evaluated. DES...

The Modification of Diet in Renal Disease (MDRD) equations provide a rapid method of assessing GFR in patients with chronic kidney disease (CKD). However, previous research indicated that modification of these equations is necessary for application in Chinese patients with CKD. The objective of this study was to modify MDRD equations on the basis of the data from the Chinese CKD population and ...

Purpose The glomerular filtration rate (GFR) is essential for carboplatin chemotherapy dosing; however, the best method to estimate GFR in patients with cancer is unknown. We identify the most accurate and least biased method. Methods We obtained data on age, sex, height, weight, serum creatinine concentrations, and results for GFR from chromium-51 (51Cr) EDTA excretion measurements (51Cr-EDTA ...

BACKGROUND We aimed to assess the performance of the five creatinine-based equations commonly used for estimates of the glomerular filtration rate (eGFR), namely, the creatinine-based Chronic Kidney Disease Epidemiology Collaboration (CKD-EPIcr), Asian CKD-EPI, revised Lund-Malmö (revised LM), full age spectrum (FAS), and Korean FAS equations, in the Korean population. METHODS A total of 1,31...

1778 CLINICALCHEMISTRY, Vol. 28, No. 8, 1982 evaluation of diabetic control. Gun. Chim. Acta 104, 319-328 (1980). 12. Hankins, W. D., and Holladay, L., A temperature conversion nomogram for glycosylated hemoglobin analysis. Gun. Chim. Acta 104, 251-257 (1980). 13. Worth, R. C., Ashworth, L. A., Burrin, J. M., eta!., Column assay of haemoglobin Ai: Critical effect of temperature. Clin. Chim. Act...

Background: Bland and Altman have published their method of differences in 1986 in the Lancet to draw their method to the attention of medical professionals. Bland and Altman always have pointed out that their method of differences is designed to detect bias between methods. Their statistical methodology has found its way among clinical chemists, but it has been criticized in 2002 that a high p...

BACKGROUND Current HIV treatment guidelines recommend using the Cockcroft-Gault equation for drug dosing adjustments. The use of newer glomerular filtration rate (GFR) estimating equations for drug dosing and the appropriateness of physician antiretroviral dosing based on estimated kidney function have not been studied in an HIV-positive population. METHODS We evaluated concordance between me...

Kidney transplantation is the treatment of choice for end-stage renal disease. The evaluation of graft function is mandatory in the management of renal transplant recipients. Glomerular filtration rate (GFR), is generally considered the best index of graft function and also a predictor of graft and patient survival. However GFR measurement using inulin clearance, the gold standard for its measu...

OBJECTIVE To assess early nephrotoxicity of CDDP (Cis-diamminedichloroplatinum) manifested by a decline in the glomerular filtration rate (GFR) estimated by plasma two sample clearance method (PSC 2) after 99mTc-DTPA injection. STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY Department of Nuclear Medicine, Karachi Institute of Radiotherapy and Nuclear Medicine, Karachi, from Sep...

Glomerular filtration rate (GFR) is the most useful indicator of kidney function and kidney disease progression. Measurement of GFR is laborious to perform clinically, as it is time-consuming and costly, with turn-around time for results being too slow for many clinical situations encountered in the hospital and outpatient setting. Thus, there is great interest in developing GFR estimating form...