Background and objectives: Long-term exposure to opiates induces tolerance to the analgesic effect. The chronic use of opioids in glia cells produces pro-inflammatory mediators such as Tissue Necrosis Factor α and interleukins. Regarding the reports on Ocimum basilicum (Family: Lamiaceae) which has antioxidant and anti-inflammatory effects, it is probable that it could...

Background: Considering the increasing resistance of bacteria to antibiotics and the presence of antibacterial agents in plantsObjectives: the aim of this study was the antimicrobial and antibiofilm activity of Tecomella undulata and Momordica charantia ethanol and aceton leaf extract on antibiotic resistance Acinetobacter baumannii.Methods: The leaves of Tecomella undulata and Momo...

Background: Considering the increasing resistance of bacteria to antibiotics and the presence of antibacterial agents in plantsObjectives: the aim of this study was the antimicrobial and antibiofilm activity of Tecomella undulata and Momordica charantia ethanol and aceton leaf extract on antibiotic resistance Acinetobacter baumannii.Methods: The leaves of Tecomella undulata and Momo...

Six groups of adult Sprague-Dawley rats were orally administered with a variety of treatments to elucidate their cytoprotective effects. Absolute ethanol combined with HCl was used to induce gastric lesions in rats. Aqueous and ethanol extracts of Chromolaena odorata, a famous folk herb for treating skin wounds were evaluated to determine their protective effect on gastric mucosa. In this study...

Cimicifugae rhizoma (C. rhizoma) called Shengma (Chinese), Seungma (Korean), and Shoma (Japanese) is primarily derived from Cimicifuga heracleifolia Komarov or Cimicifuga foetida Linnaeus. C. rhizoma is used for anti-inflammatory, analgesic, antipyretic remedy and alternative for hormone replacement therapy. The aim of this study was to determine the dose-dependent anti-inflammatory and tumor s...

background: alcoholic mothers who consume ethanol give birth to infants with high percentage of hepatic diseases. alcohol can cause cellular damage in different tissues, including liver. finding a drug which is effective and efficient in reducing ethanol misuse consequences during pregnancy can assist the decrease of harmful effects of this habit. objective: this research aims to study the effe...

Phytochemical screening of Geigeria alata leaves revealed the presence of flavonoids,tannins and alkaloids. A flavonoid compound Iwas isolated from ethanol extract by column and thin layer chromatography and its structure was established on the basis of its spectral data (IR, UV, NMR and MS). Compound I and different fractions (ethanol, chloroform, nbutanol and ethyl acetate) of Geigeria alata ...

Objective: Nymphaea alba is a medicinal plant used in tropical regions for its genital, gastrointestinal and bronchial activities. In the present study, the probable effect of the ethanol extract of the rhizome on rat uterus in the presence of standard antagonists like salbutamol and atropine and a uterine stimulant like oxytocin were examined. Methods: This work examined the effect of the etha...

The objective of the current research work was to evaluate the neuroprotective effect of the ethanol extract of Scutellaria baicalensis (S.B.) on the excitotoxic neuronal cell death in primary rat cortical cell cultures. The inhibitory effects of the extract were qualitatively and quantitatively estimated by phase-contrast microscopy and lactate dehydrogenase (LDH) assays. The extract exhibited...

Currently, >35 Saudi Arabian medicinal plants are traditionally used for various liver disorders without a scientific rationale. This is the first experimental evaluation of the anti-hepatitis B virus (HBV) potential of the total ethanolic and sequential organic extracts of 60 candidate medicinal plants. The extracts were tested for toxicity on HepG2.2.15 cells and cytotoxicity concentration (C...