This paper presents the fabrication of controlled release devices for anticancer drug paclitaxel using supercritical antisolvent method. The thermodynamic and hydrodynamic effects during supercritical antisolvent process on the particle properties obtained were investigated. Scanning electron microscopy was employed to study particle sizes and morphologies achieved. It was observed that increas...

This study investigates the differences between the predictions of various properties of rigid and flexible simple point charge water models at supercritical conditions. Molecular dynamics simulations were conducted for supercritical water in a temperature range of 773-1073 K and densities in the range 115-659 kg/m3. We present thermodynamic data, pair correlation functions, selfdiffusivity, po...

A detailed investigation of ultrafast photoinduced electron transfer (ET) in a mixed valence compound ((NH3)5RuNCRu(CN)5; RuRu) in formamide, ethylene glycol, and glycerol was performed using variable wavelength femtosecond pump-probe spectroscopy over a broad range of pump and probe wavelengths. The ET kinetics were monitored by observing recovery of the ground state population. The spectra ar...

On the basis of X-ray diffraction and mass spectrometric analysis of carrier γ-Al2O3 and catalysts CuCl2/CuCl on its surface, the chemical structure of the active centers of two types oxidative chlorination catalysts applied and permeated type of industrial brands "Harshow" and "MEDС-B" was investigated. On the basis of quantum-mechanical theory of the crystal, field complexes were detected by ...

In a research project of EADS Airbus and the TUHH a system simulation of a cooling system is to be realized, using the refrigerant carbondioxid (CO2). The simulation models of the cooling cycle are created using Modelica and the thermohydraulic model library ThermoFlow. Modelica and the model library operate since spring 2000. The project will be finished untill the end of 2002. For the structu...

The work is based on the drying of PVDF-HFP gels with a procedure assisted by supercritical CO2 to obtain nano-sized porous membranes at high quality/low cost ratio. Poly(vinylidene fluoride) (PVDF) as homopolymer or copolymer with hexafluoropropylene (PVDF-HFP) is a very interesting material largely used in catalytic membrane reactors, chemical and biomedical applications and various filtratio...

The enantiomer separation by supercritical fl uid chromatography (SFC) of six profen drugs was investigated on the new generation of chiral columns from Daicel Corporation, that are packed with the immobilized polysaccharide-derived chiral stationary phases CHIRALPAK IA, CHIRALPAK IB, CHIRALPAK IC, and CHIRALPAK ID. Methanol, ethanol, 2-propanol and acetonitrile were used in combination with tr...

In this paper, we demonstrate biphasic microfluidic droplets with broadly tunable internal structures, from simple near-equilibrium drop-in-drop morphologies to complex yet uniform non-equilibrium steady-state structures. The droplets contain an aqueous mixture of poly(ethylene glycol) (PEG) and dextran and are dispensed into an immiscible oil in a microfluidic T-junction device. Above a certai...

In this paper, the simplified local density (SLD) theory is combined with the ESD equation of state to study the adsorption of solutes from supercritical carbon dioxide onto activated carbon. Firstly the model was applied to fit the adsorption of toluene+CO2 and benzene+CO2 by using only two temperature-independent parameters. It was shown that this theoretical model is capable of describing th...