In vitro electrophysiological data suggest that interleukin-1 may promote non-rapid eye movement sleep by inhibiting spontaneous firing of wake-active serotonergic neurons in the dorsal raphe nucleus (DRN). Interleukin-1 enhances GABA inhibitory effects. DRN neurons are under an inhibitory GABAergic control. This study aimed to test the hypothesis that interleukin-1 inhibits DRN serotonergic ne...

Chronic experimental allergic encephalomyelitis (CEAE) is a well-established animal model for the human syndrome, multiple sclerosis. CEAE has striking histological, electrophysiological and clinical analogies with multiple sclerosis and is a valuable animal model for the preclinical pharmacotherapeutical development of new putative therapeutic agents. In this paper, we describe a neurotrophic ...

FELDMAN, SHAUL, CHARLES S. VAN DER HEIDE AND ROBERT W. PORTER. Evoked potentials in the hypothalamus. Am. J. Physiol. rg6(6): I 163-1167. I g5g.-The distribution and some properties of the evoked potentials in the hypothalamus from stimulation of the sciatic nerve were investigated in 60 cats. In the posterior and lateral hypothalamus biphasic positive-negative responses of 7-1 o msec. latency ...

We re-examined 21 patients with suspected multiple sclerosis, seven classified as probable and 14 as possible cases. At the first investigation all patients but two had abnormal visual evoked potentials and somatosensory evoked potentials, or both. All but three had an increased intracerebral production of immunoglobulin G expressed by the cerebrospinal fluid IgG index. At follow-up two to four...

People with synaesthesia have been reported to show atypical electrophysiological responses certain simple sensory stimuli, even if these stimuli are not inducers of synaesthesia. However, it is unclear whether this constitutes a neural marker that relatively specific or reflects some other trait co-occurs synaesthesia, but it. One candidate sensitivity (e.g., strong aversion lights and sounds,...

  Introduction:   The daf is a large Persian frame drum used as a musical instrument in both popular and classical music which can induce a percussive sound at low frequencies (146–290 Hz) with peaks of up to 130 dBspl. The percussive sounds have a power distribution in the region of saccular sensitivity. In view of the saccular stimulation by sound in humans, we decided to use cervical vestibu...

In this study, we investigated corticospinal excitability during mental simulation of a leg extension movement with the technique of transcranial magnetic stimulation. Motor evoked potentials were recorded in both knee extensors (quadriceps) and flexors (biceps femoris) in 19 trained participants (healthy volunteers). The amplitude and latency of motor evoked potentials were compared in three c...