نتایج جستجو برای: excessive erythrocytosis
تعداد نتایج: 54835 فیلتر نتایج به سال:
The molecular basis of the erythrocytosis group of red cell disorders is incompletely defined. Some cases are due to dysregulation of erythropoietin (Epo) synthesis. The hypoxia inducible transcription factor (HIF) tightly regulates Epo synthesis. HIF in turn is regulated through its alpha subunit, which under normoxic conditions is hydroxylated on specific prolines and targeted for degradation...
A 78-year-old man on hemodialysis presented to our hospital with erythrocytosis. He had started hemodialysis 4 years previously, with a hemoglobin level of 9.8 g/dL, and was administered erythropoiesis stimulating agents and ferrous sulfate. Two years previously, his hemoglobin level increased to 14.5 g/dL and the treatment for anemia was discontinued. He continued hemodialysis thrice weekly; h...
In 1954 a then 31 -yr-old male was found to have erythrocytosis. Over the ensuing decade he received 72 mCi 32P. In 1964 his daughters were found to have erythrocytosis. Further investigation led to the discovery of hemoglobin Yakima, a variant with high oxygen affinity. He received no further therapy and was well until 1975, when he developed the preleu. kemic syndrome. Within 12 mo he develop...
Detection of the JAK2V617F mutation is of major help in the diagnosis of myeloproliferative neoplasms (MPNs). Techniques using allele-specific quantitative PCR (AS-qPCR) can reliably and consistently detect down to 0.001% mutated alleles. Moreover, a study of healthy blood donors has shown that the maximum JAK2V617F value in 200 subjects was 0.035%. In practice, a positivity threshold of 1% is ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید