BACKGROUND Vitiligo is an acquired pigmentary skin disorder affecting 0.1-4% of the general population. The nails may be affected in patients with an autoimmune disease such as psoriasis, and in those with alopecia areata. It has been suggested that nail abnormalities should be apparent in vitiligo patients. OBJECTIVE We sought to document the frequency and clinical presentation of nail abnor...

Autoimmune diseases are caused by loss of self-tolerance resulting in both humoral and cell-driven targeting healthy tissue immune cells. Different cytokines thought to drive different autoimmune skin (e.g. IL17 psoriasis, Type-I interferon cutaneous lupus erythematosus (CLE), Type-II vitiligo), yet similar cytokine signatures present across diseases. For a direct systematic comparison disease ...

BACKGROUND In vitiligo, melanocytes are gradually lost in depigmented macules of the skin. The disappearance of melanocytes has, however, not been clearly observed and consequently the aetiology of the disease (autoimmune, neural, cytotoxic) is still elusive. The starting point of vitiligo macules is frequently determined by local conditions such as wounds and excoriations, but may also follow ...