In normal and lathyritic chick embryos bone collagen was synthesized primarily in the periosteum of the femurs, and was organized as radioactive spicules in these bones. Saline extraction of the lathyritic bones removed the radioactive spicules, although they eventually seemed to become non-extractable. Normal bone seemed to be unaffected by saline extraction. Marked variation in the degree of ...

Priming fluids for cardiopulmonary bypass have been extremely varied, with resultant hemodilution. Furthermore, major surgeries utilizing cardiopulmonary bypass require multiple postoperative transfusions of blood and blood products. The appeal of having a readily available blood substitute for major cardiovascular and neurosurgical operations could prove to be a life saver, while also elimin...

The problem of the etiology of tumors, and in particular of carcinoma, has been investigated for a great many years, but has not yet been solved. Many suggestions have been offered, among which Virchow’s and Cohnheim’s are especially prominent; both of these, however, were the result of clinical experience rather than of experimental study; hence, the adherents of these hypotheses have tried su...

The principles governing the passage of high frequency currents through various conductors have been discussed and exemplified in experiments done on both non-living and living bodies. In Part I it was shown: (1) That the current takes the path of least electrical resistance rather than the shortest path; (2) that maximal heating occurs at the point of greatest concentration of the lines of cur...