Introduction RNA genomes versus DNA genomes Quasispecies theory and virus adaptation RNA Processing in the Nucleus Capping Splicing Polyadenylation and Nuclear Export Cytoplasmic Transcription Translation in Eukaryotes Post-transcriptional Control Leaky Scanning Ribosomal Frameshifting Stop Codon Readthrough Concluding Remarks

We engineered a photoactivatable system for rapidly and reversibly exporting proteins from the nucleus by embedding a nuclear export signal in the LOV2 domain from phototropin 1. Fusing the chromatin modifier Bre1 to the photoswitch, we achieved light-dependent control of histone H2B monoubiquitylation in yeast, revealing fast turnover of the ubiquitin mark. Moreover, this inducible system allo...

This paper provides a direct test of how fixed export costs and productivity jointly determine firm-level export behavior. Using Chilean data, we construct indices of fixed export costs for each industry-region-year triplet and match them to domestic firms. Our empirical results show that firms facing higher fixed export costs are less likely to export, while those with higher productivity expo...

Recent years have seen a surge of interest in distributed residential batteries for households with renewable generation. Yet, assuring battery assets are profitable their owners requires complex optimisation the asset and additional revenue sources, such as novel ways to access wholesale energy markets. In this paper, we propose framework which market bids placed on forward markets by an aggre...

The mRNA nuclear export receptor Mex67/Mtr2 is recruited to mRNAs through RNA-binding adaptors, including components of the THO/TREX complex that couple transcription to mRNA export. Here we show that the ubiquitin-associated (UBA) domain of Mex67 is not only required for proper nuclear export of mRNA but also contributes to recruitment of Mex67 to transcribing genes. Our results reveal that th...